心胸血管外科
止血的管理和优化
抗纤溶药物
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis. [L'application topique de médicaments anti-fibrinolytiques pour la chirurgie cardiaque avec circulation extra-corporelle : analyse méthodique et méta-analyse.] [English, French abstract] (打开新窗口)
来源: Can J Anaesth 2009;56(3):202-12.
检索: PubMed 19247741
DOI码: 10.1007/s12630-008-9038-x
Can topical application of tranexamic acid reduce blood loss in thoracic surgery? A prospective randomised double blind investigation. (打开新窗口)
来源: Heart Lung Circ 2012;21(11):706-10.
检索: PubMed 22842057
DOI码: 10.1016/j.hlc.2012.06.016
Can local application of tranexamic acid reduce post-coronary bypass surgery blood loss? A randomized controlled trial. (打开新窗口)
来源: J Cardiothorac Surg 2009;4:25.
检索: PubMed 19538741
DOI码: 10.1186/1749-8090-4-25
Current status of pharmacologic therapies in patient blood management. (打开新窗口)
来源: Anesth Analg 2013;116(1):15-34.
检索: PubMed 23223098
DOI码: 10.1213/ANE.0b013e318273f4ae
The effect of epsilon-aminocaproic acid and aprotinin on fibrinolysis and blood loss in patients undergoing primary, isolated coronary artery bypass surgery: a randomized, double-blind, placebo-controlled, noninferiority trial. (打开新窗口)
来源: Anesth Analg 2009;109(1):15-24.
检索: PubMed 19535691
DOI码: 10.1213/ane.0b013e3181a40b5d
Putting the record straight on aprotinin as safe and effective: results from a mixed treatment meta-analysis of trials of aprotinin. (打开新窗口)
来源: J Thorac Cardiovasc Surg 2013;145(1):234-40.
检索: PubMed 22889481
DOI码: 10.1016/j.jtcvs.2012.07.018
The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery. (打开新窗口)
来源: Anesth Analg 2010;110(1):21-9.
检索: PubMed 19910626
DOI码: 10.1213/ANE.0b013e3181c0ea6d
Comparative evaluation of the effects of tranexamic acid and low-dose aprotinin on post-valvular heart surgery bleeding and allogenic transfusion. (打开新窗口)
来源: Interact Cardiovasc Thorac Surg 2012;15(1):23-7.
检索: PubMed 22514257
DOI码: 10.1093/icvts/ivs114
A randomized trial of tranexamic acid in combination with cell salvage plus a meta-analysis of randomized trials evaluating tranexamic acid in off-pump coronary artery bypass grafting. (打开新窗口)
来源: J Thorac Cardiovasc Surg 2006;132(3):475-80, 480.e1-8.
检索: PubMed 16935098
DOI码: 10.1016/j.jtcvs.2006.01.064
Tranexamic acid in patients undergoing coronary-artery surgery. (打开新窗口)
来源: N Engl J Med 2017;376(2):136-48.
检索: PubMed 27774838
DOI码: 10.1056/NEJMoa1606424
Aprotinin for patients exposed to clopidogrel before off-pump coronary bypass. (打开新窗口)
来源: Asian Cardiovasc Thorac Ann 2008;16(6):483-7.
检索: PubMed 18984759
DOI码: 10.1177/021849230801600611
Protective effects of tranexamic acid on clopidogrel before coronary artery bypass grafting: a multicenter randomized trial. (打开新窗口)
来源: JAMA Surg 2013;148(6):538-47.
检索: PubMed 23426385
DOI码: 10.1001/jamasurg.2013.1560
Effect of high- vs low-dose tranexamic acid infusion on need for red blood cell transfusion and adverse events in patients undergoing cardiac surgery: The OPTIMAL randomized clinical trial. (打开新窗口)
来源: JAMA. 2022;328(4):336-47.
检索: PubMed 35881121
DOI码: 10.1001/jama.2022.10725
Tranexamic acid reduces blood loss after off-pump coronary surgery: a prospective, randomized, double-blind, placebo-controlled study. (打开新窗口)
来源: Anesth Analg 2012;115(2):239-43.
检索: PubMed 21737704
DOI码: 10.1213/ANE.0b013e3182264a11
Effects of aprotinin on short-term and long-term outcomes after coronary artery bypass grafting surgery. (打开新窗口)
来源: Ann Thorac Surg 2010;89(5):1489-95.
检索: PubMed 20417766
DOI码: 10.1016/j.athoracsur.2010.02.006
Low postoperative dose of aprotinin reduces bleeding and is safe in patients receiving clopidogrel before coronary artery bypass surgery. A prospective randomized study. (打开新窗口)
来源: Interact Cardiovasc Thorac Surg 2010;10(4):545-8.
检索: PubMed 20067988
DOI码: 10.1510/icvts.2009.226613
重组活化凝血因子VII(rFVIIa)
Aortic dissection and hypothermic arrest in a Jehovah's Witness patient: a case for recombinant factor VIIa? (打开新窗口)
来源: Can J Anaesth 2006;53(4):353-6.
检索: PubMed 16575032
DOI码: 10.1007/BF03022498
Use of recombinant activated factor VII for refractory after lung transplant bleeding as an effective strategy to restrict blood transfusion and associated complications. (打开新窗口)
来源: Transfusion 2013;53(4):798-804.
检索: PubMed 22845023
DOI码: 10.1111/j.1537-2995.2012.03801.x
Recombinant activated factor VII in cardiac surgery: experience from the Australian and New Zealand Haemostasis Registry. (打开新窗口)
来源: Ann Thorac Surg 2008;85(3):836-44.
检索: PubMed 18291152
DOI码: 10.1016/j.athoracsur.2007.06.076
Repeat cardiac surgery in a Jehovah's Witness patient with thrombocytopenia. (打开新窗口)
来源: Can J Cardiol 2011;27(6):869.e7-8.
检索: PubMed 21983113
DOI码: 10.1016/j.cjca.2011.07.632
Off-label use of recombinant activated factor VII for cardiac surgical bleeding. (打开新窗口)
来源: Anesthesiology. 2023 1;139(2):197-210.
检索: PubMed 37155359
DOI码: 10.1097/ALN.0000000000004569
Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery. (打开新窗口)
来源: Circulation 2009;120(1):21-7.
检索: PubMed 19546387
DOI码: 10.1161/CIRCULATIONAHA.108.834275
Intraoperative use of recombinant activated factor VII during complex aortic surgery. (打开新窗口)
来源: J Thorac Cardiovasc Surg 2012;143(5):1198-204.
检索: PubMed 22285329
DOI码: 10.1016/j.jtcvs.2012.01.004
Off-label use of recombinant human factor VIIa. (打开新窗口)
来源: Ann Thorac Surg 2014;98(2):393-5.
检索: PubMed 25087781
DOI码: 10.1016/j.athoracsur.2014.06.007
Off-label use of recombinant activated factor VII in intractable haemorrhage after cardiovascular surgery: an observational study of practices in 23 French cardiac centres (2005-7). (打开新窗口)
来源: Eur J Cardiothorac Surg 2011;40(6):1320-7.
检索: PubMed 21550261
DOI码: 10.1016/j.ejcts.2011.03.032
Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery. (打开新窗口)
来源: Circulation 2008;118(4):331-8.
检索: PubMed 18606914
DOI码: 10.1161/CIRCULATIONAHA.108.764308
Role of recombinant factor VIIa in the treatment of intractable bleeding in vascular surgery. (打开新窗口)
来源: J Vasc Surg 2011;53(4):1032-7.
检索: PubMed 21215579
DOI码: 10.1016/j.jvs.2010.07.075
Use of activated recombinant factor VII in severe bleeding—evidence for efficacy and safety in trauma, postpartum hemorrhage, cardiac surgery, and gastrointestinal bleeding. (打开新窗口)
来源: Transfus Med Hemother 2012;39(2):139-50.
检索: PubMed 22670132
DOI码: 10.1159/000338034
Recombinant activated factor VII for postoperative hemorrhage following repair of acute type A aortic dissection. (打开新窗口)
来源: Heart Surg Forum 2010;13(5):E275-9.
检索: PubMed 20961825
DOI码: 10.1532/HSF98.20101027
Recombinant factor VIIa treatment of severe bleeding in cardiac surgery patients: a retrospective analysis of dosing, efficacy, and safety outcomes. (打开新窗口)
来源: J Cardiothorac Vasc Anesth 2009;23(1):28-33.
检索: PubMed 18948033
DOI码: 10.1053/j.jvca.2008.08.003
Recombinant activated factor VII significantly reduces transfusion requirements in cardiothoracic surgery. (打开新窗口)
来源: Drugs R D 2015;15(2):187-94.
检索: PubMed 25862216
DOI码: 10.1007/s40268-015-0093-9
Hemostatic management of severe thrombocytopenia in a patient undergoing pulmonic valve replacement. (打开新窗口)
来源: A A Case Rep 2015;5(1):3-5.
检索: PubMed 26125690
DOI码: 10.1213/XAA.0000000000000166
Treatment of excessive bleeding in Jehovah's Witness patients after cardiac surgery with recombinant factor VIIa (Novoseven®). (打开新窗口)
来源: Anesthesiology 2003;98(6):1513-5.
检索: PubMed 12766668
Recombinant activated factor VII in cardiac surgery: a systematic review. (打开新窗口)
来源: Ann Thorac Surg 2007;83(2):707-14.
检索: PubMed 17258029
DOI码: 10.1016/j.athoracsur.2006.10.033
凝血因子浓缩剂
Reduced use of allogeneic platelets through high-yield perioperative autologous plateletpheresis and reinfusion. (打开新窗口)
来源: Transfusion 2014;54(5):1348-57.
检索: PubMed 24898456
DOI码: 10.1111/trf.12463
Use of prothrombin complex concentrate for excessive bleeding after cardiac surgery. (打开新窗口)
来源: Interact Cardiovasc Thorac Surg 2012;15(3):382-9.
检索: PubMed 22623627
DOI码: 10.1093/icvts/ivs224
Reducing blood transfusion in aortic surgery: a novel approach. (打开新窗口)
来源: Ann Thorac Surg 2019;108(5):1369-75.
检索: PubMed 31255616
DOI码: 10.1016/j.athoracsur.2019.04.127
Prophylactic use of factor IX concentrate in a Jehovah's Witness patient. (打开新窗口)
来源: Ann Thorac Surg 2009;88(5):1666-8.
检索: PubMed 19853132
DOI码: 10.1016/j.athoracsur.2009.03.095
Safety and efficacy of prothrombin complex concentrate as first-line treatment in bleeding after cardiac surgery. (打开新窗口)
来源: Crit Care 2016;20:5.
检索: PubMed 26738468
DOI码: 10.1186/s13054-015-1172-6
Bloodless orthotopic heart transplantation in a Jehovah's Witness. (打开新窗口)
来源: A A Case Rep 2015;4(10):140-2.
检索: PubMed 25974419
DOI码: 10.1213/XAA.0000000000000067
State of the art - how I manage coagulopathy in cardiac surgery patients. (打开新窗口)
来源: Br J Haematol 2014;164(6):779-89.
检索: PubMed 24450971
DOI码: 10.1111/bjh.12746
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. (打开新窗口)
来源: Anesthesiology 2011;115(6):1179-91.
检索: PubMed 21970887
DOI码: 10.1097/ALN.0b013e31823497dd
Comparison of 4-factor prothrombin complex concentrate with frozen plasma for management of hemorrhage during and after cardiac surgery: a randomized pilot trial. (打开新窗口)
来源: JAMA Netw Open 2021;4(4):e213936.
检索: PubMed 33792729
DOI码: 10.1001/jamanetworkopen.2021.3936
Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study. (打开新窗口)
来源: Thromb Haemost 2009;102(1):137-44.
检索: PubMed 19572078
DOI码: 10.1160/TH08-09-0587
Fibrinogen concentrate reduces intraoperative bleeding when used as first-line hemostatic therapy during major aortic replacement surgery: results from a randomized, placebo-controlled trial. (打开新窗口)
来源: J Thorac Cardiovasc Surg 2013;145(3 Suppl):S178-85.
检索: PubMed 23410777
DOI码: 10.1016/j.jtcvs.2012.12.083
Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial. (打开新窗口)
来源: Anesthesiology 2013;118(1):40-50.
检索: PubMed 23249928
DOI码: 10.1097/ALN.0b013e3182715d4d
Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery. (打开新窗口)
来源: J Am Heart Assoc 2015;4(6):e002066.
检索: PubMed 26037084
DOI码: 10.1161/JAHA.115.002066
Fibrinogen supplementation after cardiac surgery: insights from the zero-plasma trial (ZEPLAST). (打开新窗口)
来源: Br J Anaesth 2016;116(5):618-23.
检索: PubMed 26893405
DOI码: 10.1093/bja/aev539
Bleeding in a Jehovah's Witness patient undergoing a redo aortic valve replacement controlled with cryoprecipitate and a prothrombin complex concentrate. (打开新窗口)
来源: Can J Anaesth 2012;59(3):299-303.
检索: PubMed 22161243
DOI码: 10.1007/s12630-011-9647-7
Prothrombin complex concentrate in cardiac surgery: a systematic review and meta-analysis. (打开新窗口)
来源: Ann Thorac Surg 2019;107(4):1275-83.
检索: PubMed 30458156
DOI码: 10.1016/j.athoracsur.2018.10.013
Coagulopathy after cardiopulmonary bypass in Jehovah's Witness patients: management of two cases using fractionated components and factor VIIa. (打开新窗口)
来源: Anesth Analg 2007;104(4):763-5.
检索: PubMed 17377078
DOI码: 10.1213/01.ane.0000250913.45299.f3
Haemostatic therapy in coronary artery bypass graft patients with decreased platelet function: comparison of fibrinogen concentrate with allogeneic blood products. (打开新窗口)
来源: Scand J Clin Lab Invest 2012;72(2):121-8.
检索: PubMed 22233480
DOI码: 10.3109/00365513.2011.643818
去氨加压素
Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry. (打开新窗口)
来源: Anaesthesia 2010;65(7):688-91.
检索: PubMed 20477783
DOI码: 10.1111/j.1365-2044.2010.06367.x
Platelet mapping and desmopressin reversal of platelet inhibition during emergency carotid endarterectomy. (打开新窗口)
来源: J Cardiothorac Vasc Anesth 2007;21(6):851-4.
检索: PubMed 18068065
DOI码: 10.1053/j.jvca.2007.05.009
Desmopressin for reducing postoperative blood loss and transfusion requirements following cardiac surgery in adults. (打开新窗口)
来源: Interact Cardiovasc Thorac Surg 2014;18(3):360-70.
检索: PubMed 24263581
DOI码: 10.1093/icvts/ivt491
A point-of-care assessment of the effects of desmopressin on impaired platelet function using multiple electrode whole-blood aggregometry in patients after cardiac surgery. (打开新窗口)
来源: Anesth Analg 2010;110(3):702-7.
检索: PubMed 20042444
DOI码: 10.1213/ANE.0b013e3181c92a5c
局部止血药
A comprehensive review of topical hemostatic agents: efficacy and recommendations for use. (打开新窗口)
来源: Ann Surg 2010;251(2):217-28.
检索: PubMed 20010084
DOI码: 10.1097/SLA.0b013e3181c3bcca
A review of topical hemostatic agents for use in cardiac surgery. (打开新窗口)
来源: Ann Thorac Surg 2009;88(4):1377-83.
检索: PubMed 19766855
DOI码: 10.1016/j.athoracsur.2009.02.092
Armentarium of topical hemostatic products in cardiovascular surgery: an update. (打开新窗口)
来源: Transfus Apher Sci 2014;50(1):26-31.
检索: PubMed 24412443
DOI码: 10.1016/j.transci.2013.12.009
A novel reverse thermosensitive polymer to achieve temporary atraumatic vessel occlusion in infra-popliteal bypasses. (打开新窗口)
来源: Eur J Vasc Endovasc Surg 2013;45(1):51-6.
检索: PubMed 23134676
DOI码: 10.1016/j.ejvs.2012.10.008
Drug, devices, technologies, and techniques for blood management in minimally invasive and conventional cardiothoracic surgery: a consensus statement from the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) 2011. (打开新窗口)
来源: Innovations (Phila) 2012;7(4):229-41.
检索: PubMed 23123988
DOI码: 10.1097/IMI.0b013e3182747699
Control of troublesome bleeding during repair of acute type A dissection with use of modified rapid deployment hemostat (MRDH). (打开新窗口)
来源: J Card Surg 2009;24(6):722-4.
检索: PubMed 20078720
DOI码: 10.1111/j.1540-8191.2009.00915.x
Topical haemostatic agents. (打开新窗口)
来源: Br J Surg 2008;95(10):1197-225.
检索: PubMed 18763249
DOI码: 10.1002/bjs.6357
利用血液粘弹性检测辨别外科性出血或凝血病出血
An audit of red cell and blood product use after the institution of thromboelastometry in a cardiac intensive care unit. (打开新窗口)
来源: Transfus Med 2006;16(1):31-9.
检索: PubMed 16480437
DOI码: 10.1111/j.1365-3148.2006.00645.x
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. (打开新窗口)
来源: Anesthesiology 2011;115(6):1179-91.
检索: PubMed 21970887
DOI码: 10.1097/ALN.0b013e31823497dd
Management of hemorrhage in cardiothoracic surgery. (打开新窗口)
来源: J Cardiothorac Vasc Anesth 2013;27(4 Suppl):S20-34.
检索: PubMed 23910533
DOI码: 10.1053/j.jvca.2013.05.014
Point-of-care testing: a prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients. (打开新窗口)
来源: Anesthesiology 2012;117(3):531-47.
检索: PubMed 22914710
DOI码: 10.1097/ALN.0b013e318264c644