Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H). (åbner nyt vindue)

Alshryda S, Mason J, Sarda P, Nargol A, Cooke N, Ahmad H, Tang S, Logishetty R, Vaghela M, McPartlin L, Hungin AP.

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Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total knee replacement: a randomized controlled trial (TRANX-K). (åbner nyt vindue)

Alshryda S, Mason J, Vaghela M, Sarda P, Nargol A, Maheswaran S, Tulloch C, Anand S, Logishetty R, Stothart B, Hungin AP.

Kilde‎: J Bone Joint Surg Am 2013;95(21):1961-8.

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Multimodal patient blood management program based on a three-pillar strategy: a systematic review and meta-analysis. (åbner nyt vindue)

Althoff FC, Neb H, Herrmann E, Trentino KM, Vernich L, Füllenbach C, Freedman J, Waters JH, Farmer S, Leahy MF, Zacharowski K, Meybohm P, Choorapoikayil S

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Effect of epsilon aminocaproic acid on red-cell transfusion requirements in major spinal surgery. (åbner nyt vindue)

Berenholtz SM, Pham JC, Garrett-Mayer E, Atchison CW, Kostuik JP, Cohen DB, Nundy S, Dorman T, Ness PM, Klag MJ, Pronovost PJ, Kebaish KM.

Kilde‎: Spine 2009;34(19):2096-103.

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The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty. (åbner nyt vindue)

Cankaya D, Dasar U, Satilmis AB, Basaran SH, Akkaya M, Bozkurt M.

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An evaluation of the use of topical tranexamic acid in total knee arthroplasty. (åbner nyt vindue)

Chimento GF, Huff T, Ochsner JL Jr, Meyer M, Brandner L, Babin S.

Kilde‎: J Arthroplasty 2013;28(8 Suppl):74-7.

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Hemostatic techniques reduce hospital stay following multilevel posterior cervical spine surgery. (åbner nyt vindue)

Cho SK, Yi JS, Park MS, Hu G, Zebala LP, Pahys JM, Kang MM, Lee DH, Riew KD.

Kilde‎: J Bone Joint Surg Am 2012;94(21):1952-8.

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Comparing ε-aminocaproic acid and tranexamic acid in reducing postoperative transfusions in total knee arthroplasty. (åbner nyt vindue)

Churchill JL, Puca KE, Meyer E, Carleton M, Anderson MJ.

Kilde‎: J Knee Surg 2017;30(5):460-6.

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Process improvement project using tranexamic acid is cost-effective in reducing blood loss and transfusions after total hip and total knee arthroplasty. (åbner nyt vindue)

Demos HA, Lin ZX, Barfield WR, Wilson SH, Robertson DC, Pellegrini VD Jr.

Kilde‎: J Arthroplasty 2017;32(8):2375-80.

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Comparing cost, efficacy, and safety of intravenous and topical tranexamic acid in total hip and knee arthroplasty. (åbner nyt vindue)

DiBlasi JF, Smith RP, Garavaglia J, Quedado J, Frye BM, Dietz MJ.

Kilde‎: Am J Orthop 2016;45(7):E439-43.

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Clinical and cost effectiveness-related aspects of retransfusion in total hip and knee arthroplasty. (åbner nyt vindue)

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The safety, efficacy, and cost-effectiveness of intraoperative cell salvage in metastatic spine tumor surgery. (åbner nyt vindue)

Elmalky M, Yasin N, Rodrigues-Pinto R, Stephenson J, Carroll C, Smurthwaite G, Verma R, Mohammad S, Siddique I.

Kilde‎: Spine J 2017;17(7):977-82.

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Effect of tranexamic acid on transfusion rates following total joint arthroplasty: a cost and comparative effectiveness analysis. (åbner nyt vindue)

Evangelista PJ, Aversano MW, Koli E, Hutzler L, Inneh I, Bosco J, Iorio R.

Kilde‎: Orthop Clin North Am 2017;48(2):109-15.

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Saving blood and reducing costs: updating blood transfusion practice in lower limb arthroplasty. (åbner nyt vindue)

Fenelon C, Galbraith JG, Kearsley R, Motherway C, Condon F, Lenehan B.

Kilde‎: Ir Med J 2018;111(4):730.

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Methods of bloodless care, clinical outcomes, and costs for adult patients who decline allogeneic transfusions. (åbner nyt vindue)

Frank SM, Pippa A, Sherd I, Scott AV, Lo BD, Cruz NC, Hendricks EA, Ness PM, Chaturvedi S, Resar LMS.

Kilde‎: Anesth Analg 2022;135(3):576-85.

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Radiofrequency bipolar hemostatic sealer reduces blood loss, transfusion requirements, and cost for patients undergoing multilevel spinal fusion surgery: a case control study. (åbner nyt vindue)

Frank SM, Wasey JO, Dwyer IM, Gokaslan ZL, Ness PM, Kebaish KM.

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Tranexamic acid decreases blood loss after total shoulder arthroplasty. (åbner nyt vindue)

Friedman RJ, Gordon E, Butler RB, Mock L, Dumas B.

Kilde‎: J Shoulder Elbow Surg 2016;25(4):614-8.

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Restrictive versus liberal red blood cell transfusion strategy after hip surgery: a decision model analysis of healthcare costs. (åbner nyt vindue)

Fusaro MV, Nielsen ND, Nielsen A, Fontaine MJ, Hess JR, Reed RM, DeLisle S, Netzer G.

Kilde‎: Transfusion 2017;57(2):357-66.

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Economic impact of tranexamic acid in healthy patients undergoing primary total hip and knee arthroplasty. (åbner nyt vindue)

Gillette BP, Maradit Kremers H, Duncan CM, Smith HM, Trousdale RT, Pagnano MW, Sierra RJ.

Kilde‎: J Arthroplasty 2013;28(8 Suppl):137-9.

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Cell saver for adult spinal deformity surgery reduces cost. (åbner nyt vindue)

Gum JL, Carreon LY, Kelly MP, Hostin R, Robinson C, Burton DC, Polly DW, Shaffrey CI, LaFage V, Schwab FJ, Ames CP, Kim HJ, Smith JS, Bess RS; International Spine Study Group.

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Tranexamic acid in patients with cancer undergoing endoprosthetic reconstruction: a cost analysis. (åbner nyt vindue)

Haase DR, Kimbrel B, Bombardier B, Templeton KJ, Rosenthal HG, Sweeney KR.

Kilde‎: J Am Acad Orthop Surg 2021;29(22):961-9.

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Topically applied epsilon-aminocaproic acid reduces blood loss and length of hospital stay after total knee arthroplasty. (åbner nyt vindue)

Harper RA, Sucher MG, Giordani M, Nedopil AJ.

Kilde‎: Orthopedics 2017;40(6):e1044-9.

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Does tranexamic acid reduce blood transfusion cost for primary total hip arthroplasty? A case-control study. (åbner nyt vindue)

Harris RN, Moskal JT, Capps SG.

Kilde‎: J Arthroplasty 2015;30(2):192-5.

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Tranexamic acid reduces blood loss and financial cost in primary total hip and knee replacement surgery. (åbner nyt vindue)

Irisson E, Hémon Y, Pauly V, Parratte S, Argenson JN, Kerbaul F.

Kilde‎: Orthop Traumatol Surg Res 2012;98(5):477-83.

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Using tranexamic acid for an additional 24 hours postoperatively in hip and knee arthroplasty saves money: a cost analysis from the TRAC-24 randomized control trial. (åbner nyt vindue)

Karayiannis PN, Agus A, Bryce L, Hill JC, Beverland D.

Kilde‎: Bone Jt Open 2022;3(7):536-42.

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Effect of a patient blood management programme on preoperative anaemia, transfusion rate, and outcome after primary hip or knee arthroplasty: a quality improvement cycle. (åbner nyt vindue)

Kotzé A, Carter LA, Scally AJ.

Kilde‎: Br J Anaesth 2012;108(6):943-52.

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Improved outcomes and reduced costs associated with a health-system-wide patient blood management program: a retrospective observational study in four major adult tertiary-care hospitals. (åbner nyt vindue)

Leahy MF, Hofmann A, Towler S, Trentino KM, Burrows SA, Swain SG, Hamdorf J, Gallagher T, Koay A, Geelhoed GC, Farmer SL.

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Transfusion strategy for primary knee and hip arthroplasty: impact of an algorithm to lower transfusion rates and hospital costs. (åbner nyt vindue)

Martinez V, Monsaingeon-Lion A, Cherif K, Judet T, Chauvin M, Fletcher D.

Kilde‎: Br J Anaesth 2007;99(6):794-800.

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A safe, simple and cost-effective protocol for blood transfusion in primary total knee replacement. (åbner nyt vindue)

Mehra A, Murray J, DeAlwis C.

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Are allogeneic transfusions decreasing in total knee arthroplasty patients? National Inpatient Sample 2009-2013. (åbner nyt vindue)

Mistry JB, Gwam CU, Naziri Q, Pivec R, Abraham R, Mont MA, Delanois RE.

Kilde‎: J Arthroplasty 2018;33(6):1705-12.

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Transfusion cost savings with tranexamic acid in primary total knee arthroplasty from 2009 to 2012. (åbner nyt vindue)

Moskal JT, Harris RN, Capps SG.

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The cost of post-operative shed blood salvage after total knee arthroplasty: an analysis of 1,093 consecutive procedures. (åbner nyt vindue)

Muñoz M, Ariza D, Campos A, Martín-Montañez E, Pavía J.

Kilde‎: Blood Transfus 2013;11(2):260-71.

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Cost of post-operative intravenous iron therapy in total lower limb arthroplasty: a retrospective, matched cohort study. (åbner nyt vindue)

Muñoz M, Gómez-Ramírez S, Martín-Montañez E, Naveira E, Seara J, Pavía J.

Kilde‎: Blood Transfus 2014;12(1):40-9.

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Effects of intravenous iron combined with low-dose recombinant human erythropoietin on transfusion requirements in iron-deficient patients undergoing bilateral total knee replacement arthroplasty. (åbner nyt vindue)

Na HS, Shin SY, Hwang JY, Jeon YT, Kim CS, Do SH.

Kilde‎: Transfusion 2011;51(1):118-24.

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Comparative risk of transfusion and incremental total hospitalization cost for primary unilateral, bilateral, and revision total knee arthroplasty procedures. (åbner nyt vindue)

Nichols CI, Vose JG.

Kilde‎: J Arthroplasty 2016;31(3):583-589.e1.

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The efficacy, safety, and cost-effectives of combined administration of intravenous and local tranexamic acid in the management of patients undergoing primary total hip arthroplasty: a prospective, blinded and randomized clinical study. (åbner nyt vindue)

Örs Ç, Çaylak R.

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Blood loss control with two doses of tranexamic acid in a multimodal protocol for total knee arthroplasty. (åbner nyt vindue)

Ortega-Andreu M, Pérez-Chrzanowska H, Figueredo R, Gómez-Barrena E.

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ONTraC: A 20-year history of a successfully coordinated provincewide Patient Blood Management Program: lessons learned and goals achieved. (åbner nyt vindue)

Pavenski K, Howell A, Mazer CD, Hare GMT, Freedman J.

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Cost analysis of tranexamic acid in anemic total joint arthroplasty patients. (åbner nyt vindue)

Phan DL, Ani F, Schwarzkopf R.

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Intravenous administration of tranexamic acid effectively reduces blood loss in primary total knee arthroplasty in a 610-patient consecutive case series. (åbner nyt vindue)

Pitta M, Zawadsky M, Verstraete R, Rubinstein A.

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Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety. (åbner nyt vindue)

Poeran J, Rasul R, Suzuki S, Danninger T, Mazumdar M, Opperer M, Boettner F, Memtsoudis SG.

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One intraoperative dose of tranexamic acid for patients having primary hip or knee arthroplasty. (åbner nyt vindue)

Ralley FE, Berta D, Binns V, Howard J, Naudie DD.

Kilde‎: Clin Orthop Relat Res 2010;468(7):1905-11.

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Pharmacologic hemostatic agents in total joint arthroplasty--a cost-effectiveness analysis. (åbner nyt vindue)

Ramkumar DB, Ramkumar N, Tapp SJ, Moschetti WE.

Kilde‎: J Arthroplasty 2018;33(7):2092-9.e9.

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Efficacy and cost-effectiveness of cell saving blood autotransfusion in adult lumbar fusion. (åbner nyt vindue)

Savvidou C, Chatziioannou SN, Pilichou A, Pneumaticos SG.

Kilde‎: Transfus Med 2009;19(4):202-6.

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Improved patient blood management and cost saving in hip replacement surgery through the implementation of pre-operative Sucrosomial® iron supplementation: a quality improvement assessment study. (åbner nyt vindue)

Scardino M, Di Matteo B, Martorelli F, Tanzi D, Kon E, D'Amato T.

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Use of a fibrin sealant within a blood-saving protocol in patients undergoing revision hip arthroplasty: effects on post-operative blood transfusion and healthcare-related cost analysis. (åbner nyt vindue)

Scardino M, Martorelli F, D'Amato T, Fenocchio G, Simili V, Grappiolo G, Di Matteo B, Kon E, Lagioia M

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Use of tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement. (åbner nyt vindue)

Sepah YJ, Umer M, Ahmad T, Nasim F, Chaudhry MU, Umar M.

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Increased hospital costs associated with red blood cell transfusion. (åbner nyt vindue)

Trentino KM, Farmer SL, Swain SG, Burrows SA, Hofmann A, Ienco R, Pavey W, Daly FF, Van Niekerk A, Webb SA, Towler S, Leahy MF.

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Cost benefit analysis of topical tranexamic acid in primary total hip and knee arthroplasty. (åbner nyt vindue)

Tuttle JR, Ritterman SA, Cassidy DB, Anazonwu WA, Froehlich JA, Rubin LE.

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Clinical and budget impact of treating preoperative anemia in major orthopedic surgery--a retrospective observational study. (åbner nyt vindue)

Wan S, Sparring V, Cabrales DA, Jansson KÅ, Wikman A.

Kilde‎: J Arthroplasty 2020;35(11):3084-8.

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Blood loss and cost-effectiveness of oral vs intravenous tranexamic acid in primary total hip arthroplasty: a randomized clinical trial. (åbner nyt vindue)

Wu Y, Zeng Y, Hu Q, Li M, Bao X, Zhong J, Shen B.

Kilde‎: Thromb Res 2018;171:143-8.

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Incidence and costs of bleeding-related complications in French hospitals following surgery for various diagnoses. (åbner nyt vindue)

Ye X, Lafuma A, Torreton E, Arnaud A.

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The effectiveness of reinfusion after total knee replacement. A prospective randomised controlled study. (åbner nyt vindue)

Zacharopoulos A, Apostolopoulos A, Kyriakidis A.

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Efficacy and safety of tranexamic acid in total hip replacement: a PRISMA-compliant meta-analysis of 25 randomized controlled trials. (åbner nyt vindue)

Zhu J, Zhu Y, Lei P, Zeng M, Su W, Hu Y.

Kilde‎: Medicine 2017;96(52):e9552.

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