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Otolaryngology—Head and Neck Surgery

Management and Optimization of Hemostasis

Antifibrinolytic Agents

Topical application of tranexamic acid after adenoidectomy: a double-blind, prospective, randomized, controlled study. (opens new window)

Albirmawy OA, Saafan ME, Shehata EM, Basuni AS, Eldaba AA.

Source‎: Int J Pediatr Otorhinolaryngol 2013;77(7):1139-42.

Indexed‎: PubMed 23669000

DOI‎: 10.1016/j.ijporl.2013.04.021

https://www.ncbi.nlm.nih.gov/pubmed/23669000 (opens new window)

The efficacy of preoperative oral tranexamic acid on intraoperative bleeding during rhinoplasty. (opens new window)

Eftekharian HR, Rajabzadeh Z

Source‎: J Craniofac Surg 2016;27(1):97-100.

Indexed‎: PubMed 26674898

DOI‎: 10.1097/SCS.0000000000002273

https://www.ncbi.nlm.nih.gov/pubmed/26674898 (opens new window)

Efficacy of tranexamic acid on operative bleeding in endoscopic sinus surgery: a meta-analysis and systematic review. (opens new window)

Kim DH, Kim S, Kang H, Jin HJ, Hwang SH

Source‎: Laryngoscope 2019;129(4):800-7.

Indexed‎: PubMed 30593688

DOI‎: 10.1002/lary.27766

https://www.ncbi.nlm.nih.gov/pubmed/30593688 (opens new window)

The role of antifibrinolytics in reducing blood loss during craniofacial or orthognathic surgical procedures: a meta-analysis. (opens new window)

Siotou K, Siotos C, Azizi A, Cheah MA, Seal SM, Redett RJ, Rosson GD

Source‎: J Oral Maxillofac Surg 2019;77(6):1245-60.

Indexed‎: PubMed 30796910

DOI‎: 10.1016/j.joms.2019.01.032

https://www.ncbi.nlm.nih.gov/pubmed/30796910 (opens new window)

Desmopressin

Desmopressin as a hemostatic agent to provide a dry intraoperative field in rhinoplasty. (opens new window)

Gruber RP, Zeidler KR, Berkowitz RL

Source‎: Plast Reconstr Surg 2015;135(5):1337-40.

Indexed‎: PubMed 25919247

DOI‎: 10.1097/PRS.0000000000001158

https://www.ncbi.nlm.nih.gov/pubmed/25919247 (opens new window)

Other Agents

The effect of nasal application of cocaine/adrenaline on blood loss in Le Fort I osteotomies. (opens new window)

de Lange J, Baas EM, Horsthuis RB, Booij A.

Source‎: Int J Oral Maxillofac Surg 2008;37(1):21-4.

Indexed‎: PubMed 17826960

DOI‎: 10.1016/j.ijom.2007.07.017

https://www.ncbi.nlm.nih.gov/pubmed/17826960 (opens new window)

Topical Hemostatic Agents

Effect of microporous polysaccharide hemospheres (MPH) on bleeding after endoscopic sinus surgery: randomized controlled study. (opens new window)

Antisdel JL, West-Denning JL, Sindwani R.

Source‎: Otolaryngol Head Neck Surg 2009;141(3):353-7.

Indexed‎: PubMed 19716013

DOI‎: 10.1016/j.otohns.2009.06.078

https://www.ncbi.nlm.nih.gov/pubmed/19716013 (opens new window)

Use of Floseal®, a human gelatine-thrombin matrix sealant, in surgery: a systematic review. (opens new window)

Echave M, Oyagüez I, Casado MA

Source‎: BMC Surg 2014;14:111.

Indexed‎: PubMed 25528250

DOI‎: 10.1186/1471-2482-14-111

https://www.ncbi.nlm.nih.gov/pubmed/25528250 (opens new window)

Effectiveness of chitosan-based packing in 35 patients with recalcitrant epistaxis in the context of coagulopathy. (opens new window)

Kourelis K, Shikani AH.

Source‎: Clin Otolaryngol 2012;37(4):309-13.

Indexed‎: PubMed 22925096

DOI‎: 10.1111/j.1749-4486.2012.02488.x

https://www.ncbi.nlm.nih.gov/pubmed/22925096 (opens new window)

Effect of gauze placement soaked with adrenaline at suprabullar recess on hemostasis during endoscopic sinus surgery: a randomized controlled trial. (opens new window)

Omura K, Hosokawa Y, Nomura K, Aoki S, Tochigi K, Miyashita K, Tanaka Y, Otori N, Kojima H

Source‎: Head Neck 2020;42(9):2397-404.

Indexed‎: PubMed 32385867

DOI‎: 10.1002/hed.26243

https://www.ncbi.nlm.nih.gov/pubmed/32385867 (opens new window)