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Oncology

Management and Optimization of Hemostasis

Antifibrinolytic Agents

Epsilon aminocaproic acid prevents bleeding in severely thrombocytopenic patients with hematological malignancies. (opens new window)

Antun AG, Gleason S, Arellano M, Langston AA, McLemore ML, Gaddh M, el Rassi F, Bernal-Mizrachi L, Galipeau J, Heffner LT Jr, Winton EF, Khoury HJ.

Source‎: Cancer 2013;119(21):3784-7.

Indexed‎: PubMed 23921838

DOI‎: 10.1002/cncr.28253

https://www.ncbi.nlm.nih.gov/pubmed/23921838 (opens new window)

Tranexamic acid for control of haemorrhage in acute promyelocytic leukaemia. (opens new window)

Avvisati G, ten Cate JW, Büller HR, Mandelli F.

Source‎: Lancet 1989;334(8655):122-4.

Indexed‎: PubMed 2567893

https://www.ncbi.nlm.nih.gov/pubmed/2567893 (opens new window)

Epsilon aminocaproic acid reduces transfusion requirements in patients with thrombocytopenic hemorrhage. (opens new window)

Kalmadi S, Tiu R, Lowe C, Jin T, Kalaycio M.

Source‎: Cancer 2006;107(1):136-40.

Indexed‎: PubMed 16708357

DOI‎: 10.1002/cncr.21958

https://www.ncbi.nlm.nih.gov/pubmed/16708357 (opens new window)

Aminocaproic acid use in hospitalized patients with hematological malignancy: a case series. (opens new window)

Marshall A, Li A, Drucker A, Dzik W.

Source‎: Hematol Oncol 2016;34(3):147-53.

Indexed‎: PubMed 25641349

DOI‎: 10.1002/hon.2189

https://www.ncbi.nlm.nih.gov/pubmed/25641349 (opens new window)

A controlled trial of tranexamic acid therapy for the reduction of bleeding during treatment of acute myeloid leukemia. (opens new window)

Shpilberg O, Blumenthal R, Sofer O, Katz Y, Chetrit A, Ramot B, Eldor A, Ben-Bassat I.

Source‎: Leuk Lymphoma 1995;19(1-2):141-4.

Indexed‎: PubMed 8574160

DOI‎: 10.3109/10428199509059668

https://www.ncbi.nlm.nih.gov/pubmed/8574160 (opens new window)

Recombinant Activated Factor VII (rFVIIa)

Use of Novoseven for arsenic trioxide-induced bleeding in PML. (opens new window)

Alimoghaddam K, Ghavamzadeh A, Jahani M.

Source‎: Am J Hematol 2006;81(9):720.

Indexed‎: PubMed 16804937

DOI‎: 10.1002/ajh.20713

https://www.ncbi.nlm.nih.gov/pubmed/16804937 (opens new window)

The potential role of recombinant activated FVII in the management of critical hemato-oncological bleeding: a systematic review. (opens new window)

Franchini M, Veneri D, Lippi G.

Source‎: Bone Marrow Transplant 2007;39(12):729-35.

Indexed‎: PubMed 17417659

DOI‎: 10.1038/sj.bmt.1705670

https://www.ncbi.nlm.nih.gov/pubmed/17417659 (opens new window)

Effective hemostasis with rFVIIa treatment in two patients with severe thrombocytopenia and life-threatening hemorrhage. (opens new window)

Gerotziafas GT, Zervas C, Gavrielidis G, Tokmaktsis A, Hatjiharissi E, Papaioannou M, Lazaridou A, Constantinou N, Samama MM, Christakis J.

Source‎: Am J Hematol 2002;69(3):219-22.

Indexed‎: PubMed 11891811

https://www.ncbi.nlm.nih.gov/pubmed/11891811 (opens new window)

Use of recombinant activated factor VII in a Jehovah's Witness patient. (opens new window)

Hsieh A, Cheong I.

Source‎: Am J Emerg Med 2007;25(9):1085.e1-2.

Indexed‎: PubMed 18022514

DOI‎: 10.1016/j.ajem.2007.03.007

https://www.ncbi.nlm.nih.gov/pubmed/18022514 (opens new window)

Clinical experience with recombinant factor VIIa in patients with thrombocytopenia. (opens new window)

Kristensen J, Killander A, Hippe E, Helleberg C, Ellegard J, Holm M, Kutti J, Mellqvist UH, Johansson JE, Glazer S, Hedner U.

Source‎: Haemostasis 1996;26 Suppl 1:159-64.

Indexed‎: PubMed 8904193

https://www.ncbi.nlm.nih.gov/pubmed/8904193 (opens new window)

Coagulation Factor Concentrates

Management of bleeding complications of hematologic malignancies. (opens new window)

Green D.

Source‎: Semin Thromb Hemost 2007;33(4):427-34.

Indexed‎: PubMed 17525900

DOI‎: 10.1055/s-2007-976178

https://www.ncbi.nlm.nih.gov/pubmed/17525900 (opens new window)

Management of bleeding in patients with advanced cancer. (opens new window)

Pereira J, Phan T.

Source‎: Oncologist 2004;9(5):561-70.

Indexed‎: PubMed 15477642

DOI‎: 10.1634/theoncologist.9-5-561

https://www.ncbi.nlm.nih.gov/pubmed/15477642 (opens new window)

Desmopressin

Desmopressin and other synthetic vasopressin analogues in cancer treatment. (opens new window)

Gomez DE, Ripoll GV, Girón S, Alonso DF.

Source‎: Bull Cancer 2006;93(2):E7-12.

Indexed‎: PubMed 16517412

https://www.ncbi.nlm.nih.gov/pubmed/16517412 (opens new window)