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Oral and Maxillofacial Surgery

Management and Optimization of Hemostasis

Antifibrinolytic Agents

The effect of tranexamic acid on blood loss during orthognathic surgery: a randomized controlled trial. (opens new window)

Choi WS, Irwin MG, Samman N.

Source‎: J Oral Maxillofac Surg 2009;67(1):125-33.

Indexed‎: PubMed 19070758

DOI‎: 10.1016/j.joms.2008.08.015

https://www.ncbi.nlm.nih.gov/pubmed/19070758 (opens new window)

Effect of tranexamic acid irrigation on perioperative blood loss during orthognathic surgery: a double-blind, randomized controlled clinical trial. (opens new window)

Eftekharian H, Vahedi R, Karagah T, Tabrizi R

Source‎: J Oral Maxillofac Surg 2015;73(1):129-33.

Indexed‎: PubMed 25443384

DOI‎: 10.1016/j.joms.2014.07.033

https://www.ncbi.nlm.nih.gov/pubmed/25443384 (opens new window)

The efficacy and safety of tranexamic acid in cranio-maxillofacial and plastic surgery. (opens new window)

Murphy GR, Glass GE, Jain A

Source‎: J Craniofac Surg 2016;27(2):374-9.

Indexed‎: PubMed 26967076

DOI‎: 10.1097/SCS.0000000000002250

https://www.ncbi.nlm.nih.gov/pubmed/26967076 (opens new window)

Prevention of bleeding in orthognathic surgery--a systematic review and meta-analysis of randomized controlled trials. (opens new window)

Olsen JJ, Skov J, Ingerslev J, Thorn JJ, Pinholt EM

Source‎: J Oral Maxillofac Surg 2016;74(1):139-50.

Indexed‎: PubMed 26073131

DOI‎: 10.1016/j.joms.2015.05.031

https://www.ncbi.nlm.nih.gov/pubmed/26073131 (opens new window)

Evaluation of the efficacy of tranexamic acid on blood loss in orthognathic surgery. A prospective, randomized clinical study. (opens new window)

Sankar D, Krishnan R, Veerabahu M, Vikraman B.

Source‎: Int J Oral Maxillofac Surg 2012;41(6):713-7.

Indexed‎: PubMed 22340993

DOI‎: 10.1016/j.ijom.2012.01.008

https://www.ncbi.nlm.nih.gov/pubmed/22340993 (opens new window)

Tranexamic acid is associated with improved operative field in orthognathic surgery. (opens new window)

Sharma H, Arora S, Bhatia N, Rattan V, Sethi S

Source‎: J Oral Maxillofac Surg 2020;78(9):1509-17.

Indexed‎: PubMed 32497489

DOI‎: 10.1016/j.joms.2020.04.037

https://www.ncbi.nlm.nih.gov/pubmed/32497489 (opens new window)

The role of antifibrinolytics in reducing blood loss during craniofacial or orthognathic surgical procedures: a meta-analysis. (opens new window)

Siotou K, Siotos C, Azizi A, Cheah MA, Seal SM, Redett RJ, Rosson GD

Source‎: J Oral Maxillofac Surg 2019;77(6):1245-60.

Indexed‎: PubMed 30796910

DOI‎: 10.1016/j.joms.2019.01.032

https://www.ncbi.nlm.nih.gov/pubmed/30796910 (opens new window)

Aprotinin reduces blood loss and the need for transfusion in orthognathic surgery. (opens new window)

Stewart A, Newman L, Sneddon K, Harris M.

Source‎: Br J Oral Maxillofac Surg 2001;39(5):365-70.

Indexed‎: PubMed 11601817

DOI‎: 10.1054/bjom.2001.0664

https://www.ncbi.nlm.nih.gov/pubmed/11601817 (opens new window)

Desmopressin

Evaluation of hemorrhage depressors on blood loss during orthognathic surgery: a retrospective study. (opens new window)

Zellin G, Rasmusson L, Pålsson J, Kahnberg KE.

Source‎: J Oral Maxillofac Surg 2004;62(6):662-6.

Indexed‎: PubMed 15170275

https://www.ncbi.nlm.nih.gov/pubmed/15170275 (opens new window)

Other Agents

The effect of nasal application of cocaine/adrenaline on blood loss in Le Fort I osteotomies. (opens new window)

de Lange J, Baas EM, Horsthuis RB, Booij A.

Source‎: Int J Oral Maxillofac Surg 2008;37(1):21-4.

Indexed‎: PubMed 17826960

DOI‎: 10.1016/j.ijom.2007.07.017

https://www.ncbi.nlm.nih.gov/pubmed/17826960 (opens new window)

Topical Hemostatic Agents

Clinical applications of fibrin sealants. (opens new window)

Fattahi T, Mohan M, Caldwell GT.

Source‎: J Oral Maxillofac Surg 2004;62(2):218-24.

Indexed‎: PubMed 14762755

https://www.ncbi.nlm.nih.gov/pubmed/14762755 (opens new window)

Hemostasis of oral surgery wounds with the HemCon Dental Dressing. (opens new window)

Malmquist JP, Clemens SC, Oien HJ, Wilson SL.

Source‎: J Oral Maxillofac Surg 2008;66(6):1177-83.

Indexed‎: PubMed 18486782

DOI‎: 10.1016/j.joms.2007.12.023

https://www.ncbi.nlm.nih.gov/pubmed/18486782 (opens new window)

Topical hemostatic agents: what the oral and maxillofacial surgeon needs to know. (opens new window)

Vezeau PJ

Source‎: Oral Maxillofac Surg Clin North Am 2016;28(4):523-32.

Indexed‎: PubMed 27745620

DOI‎: 10.1016/j.coms.2016.06.007

https://www.ncbi.nlm.nih.gov/pubmed/27745620 (opens new window)