Sickle Cell Disease (Pediatrics)
Management of Vaso-Occlusive Crisis and Acute Chest Syndrome
Pain Management
What is the best pharmacologic treatment for sickle cell disease pain crises? (opens new window)
Source: Ann Emerg Med 2012;59(6):515-6.
Indexed: PubMed 22221839
DOI: 10.1016/j.annemergmed.2011.11.026
https://www.ncbi.nlm.nih.gov/pubmed/22221839 (opens new window)
Multi-modal intervention and prospective implementation of standardized sickle cell pain admission orders reduces 30-day readmission rate. (opens new window)
Source: Pediatr Blood Cancer 2009;53(3):401-5.
Indexed: PubMed 19422031
DOI: 10.1002/pbc.22048
https://www.ncbi.nlm.nih.gov/pubmed/19422031 (opens new window)
Reduction of painful vaso-occlusive crisis of sickle cell anaemia by tinzaparin in a double-blind randomized trial. (opens new window)
Source: Thromb Haemost 2007;98(2):392-6.
Indexed: PubMed 17721622
https://www.ncbi.nlm.nih.gov/pubmed/17721622 (opens new window)
Hydration Therapy (Fluid Management)
Fluid replacement therapy for acute episodes of pain in people with sickle cell disease. (opens new window)
Source: Cochrane Database Syst Rev 2012;(6):CD005406.
Indexed: PubMed 22696351
DOI: 10.1002/14651858.CD005406.pub3
https://www.ncbi.nlm.nih.gov/pubmed/22696351 (opens new window)
Oxygen Supplementation
Guidelines for the management of the acute painful crisis in sickle cell disease. (opens new window)
Source: Br J Haematol 2003;120(5):744-52.
Indexed: PubMed 12614204
https://www.ncbi.nlm.nih.gov/pubmed/12614204 (opens new window)
Antibiotic and Respiratory Therapy
The use of incentive spirometry in pediatric patients with sickle cell disease to reduce the incidence of acute chest syndrome. (opens new window)
Source: J Pediatr Hematol Oncol 2011;33(6):415-20.
Indexed: PubMed 21792036
DOI: 10.1097/MPH.0b013e31821ed4ce
https://www.ncbi.nlm.nih.gov/pubmed/21792036 (opens new window)
Safety of purified poloxamer 188 in sickle cell disease: phase I study of a non-ionic surfactant in the management of acute chest syndrome. (opens new window)
Source: Hemoglobin 2004;28(2):85-102.
Indexed: PubMed 15182051
https://www.ncbi.nlm.nih.gov/pubmed/15182051 (opens new window)
Beneficial effect of intravenous dexamethasone in children with mild to moderately severe acute chest syndrome complicating sickle cell disease. (opens new window)
Source: Blood 1998;92(9):3082-9.
Indexed: PubMed 9787142
https://www.ncbi.nlm.nih.gov/pubmed/9787142 (opens new window)
A short course of prednisone in the management of acute chest syndrome of sickle cell disease. (opens new window)
Source: J Pediatr Hematol Oncol 2010;32(3):e91-4.
Indexed: PubMed 20216237
DOI: 10.1097/MPH.0b013e3181c29c52
https://www.ncbi.nlm.nih.gov/pubmed/20216237 (opens new window)
A randomized, placebo-controlled trial of arginine therapy for the treatment of children with sickle cell disease hospitalized with vaso-occlusive pain episodes. (opens new window)
Source: Haematologica 2013;98(9):1375-82.
Indexed: PubMed 23645695
DOI: 10.3324/haematol.2013.086637
https://www.ncbi.nlm.nih.gov/pubmed/23645695 (opens new window)
Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease. (opens new window)
Source: JAMA 2003;289(9):1136-42.
Indexed: PubMed 12622584
https://www.ncbi.nlm.nih.gov/pubmed/12622584 (opens new window)
Predictors of bacteremia in febrile children with sickle cell disease. (opens new window)
Source: J Pediatr Hematol Oncol 2002;24(4):279-83.
Indexed: PubMed 11972096
https://www.ncbi.nlm.nih.gov/pubmed/11972096 (opens new window)