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Talasemia beta mayor

Inducción farmacológica de síntesis de hemoglobina fetal

Tratamiento con hidroxiurea (hidroxicarbamida)

Efficacy of hydroxyurea in providing transfusion independence in β-thalassemia. (abre una nueva ventana)

Ansari SH, Shamsi TS, Ashraf M, Perveen K, Farzana T, Bohray M, Erum S, Mehboob T.

Fuente‎: J Pediatr Hematol Oncol 2011;33(5):339-43.

Indexado en‎: PubMed 21602718

DOI‎: 10.1097/MPH.0b013e31821b0770

https://www.ncbi.nlm.nih.gov/pubmed/21602718 (abre una nueva ventana)

Decreased transfusion needs associated with hydroxyurea therapy in Algerian patients with thalassemia major or intermedia. (abre una nueva ventana)

Bradai M, Pissard S, Abad MT, Dechartres A, Ribeil JA, Landais P, de Montalembert M.

Fuente‎: Transfusion 2007;47(10):1830-6.

Indexado en‎: PubMed 17880608

DOI‎: 10.1111/j.1537-2995.2007.01399.x

https://www.ncbi.nlm.nih.gov/pubmed/17880608 (abre una nueva ventana)

Hydroxyurea increases hemoglobin F levels and improves the effectiveness of erythropoiesis in beta-thalassemia/hemoglobin E disease. (abre una nueva ventana)

Fucharoen S, Siritanaratkul N, Winichagoon P, Chowthaworn J, Siriboon W, Muangsup W, Chaicharoen S, Poolsup N, Chindavijak B, Pootrakul P, Piankijagum A, Schechter AN, Rodgers GP.

Fuente‎: Blood 1996;87(3):887-92.

Indexado en‎: PubMed 8562958

https://www.ncbi.nlm.nih.gov/pubmed/8562958 (abre una nueva ventana)

Genotype-phenotype relationship of patients with β-thalassemia taking hydroxyurea: a 13-year experience in Iran. (abre una nueva ventana)

Karimi M, Haghpanah S, Farhadi A, Yavarian M.

Fuente‎: Int J Hematol 2012;95(1):51-6.

Indexado en‎: PubMed 22180324

DOI‎: 10.1007/s12185-011-0985-6

https://www.ncbi.nlm.nih.gov/pubmed/22180324 (abre una nueva ventana)

Clinical experience with fetal hemoglobin induction therapy in patients with β-thalassemia. (abre una nueva ventana)

Musallam KM, Taher AT, Cappellini MD, Sankaran VG.

Fuente‎: Blood 2013;121(12):2199-212.

Indexado en‎: PubMed 23315167

DOI‎: 10.1182/blood-2012-10-408021

https://www.ncbi.nlm.nih.gov/pubmed/23315167 (abre una nueva ventana)

A randomised double-blind placebo-controlled clinical trial of oral hydroxyurea for transfusion-dependent β-thalassaemia. (abre una nueva ventana)

Yasara N, Wickramarathne N, Mettananda C, Silva I, Hameed N, Attanayaka K, Rodrigo R, Wickramasinghe N, Perera L, Manamperi A, Premawardhena A, Mettananda S

Fuente‎: Sci Rep. 2022;12(1):2752.

Indexado en‎: PubMed 35177777

DOI‎: 10.1038/s41598-022-06774-8

https://pubmed.ncbi.nlm.nih.gov/35177777/ (abre una nueva ventana)

Response to hydroxyurea treatment in Iranian transfusion-dependent beta-thalassemia patients. (abre una nueva ventana)

Yavarian M, Karimi M, Bakker E, Harteveld CL, Giordano PC.

Fuente‎: Haematologica 2004;89(10):1172-8.

Indexado en‎: PubMed 15477200

https://www.ncbi.nlm.nih.gov/pubmed/15477200 (abre una nueva ventana)

Hydroxyurea therapy in 49 patients with major beta-thalassemia. (abre una nueva ventana)

Zamani F, Shakeri R, Eslami SM, Razavi SM, Basi A.

Fuente‎: Arch Iran Med 2009;12(3):295-7.

Indexado en‎: PubMed 19400608

https://www.ncbi.nlm.nih.gov/pubmed/19400608 (abre una nueva ventana)

Eritropoyetina recombinante (sola o combinada con otros agentes)

Induction of fetal hemoglobin synthesis with recombinant human erythropoietin in anemic patients with heterozygous beta-thalassemia during pregnancy. (abre una nueva ventana)

Breymann C, Fibach E, Visca E, Huettner C, Huch A, Huch R.

Fuente‎: J Matern Fetal Med 1999;8(1):1-7.

Indexado en‎: PubMed 10052837

DOI‎: 10.1002/(SICI)1520-6661(199901/02)8:1<1::AID-MFM1>3.0.CO;2-O

https://www.ncbi.nlm.nih.gov/pubmed/10052837 (abre una nueva ventana)

Treatment of beta-thalassemia patients with recombinant human erythropoietin: effect on transfusion requirements and soluble adhesion molecules. (abre una nueva ventana)

Chaidos A, Makis A, Hatzimichael E, Tsiara S, Gouva M, Tzouvara E, Bourantas KL.

Fuente‎: Acta Haematol 2004;111(4):189-95.

Indexado en‎: PubMed 15153710

DOI‎: 10.1159/000077551

https://www.ncbi.nlm.nih.gov/pubmed/15153710 (abre una nueva ventana)

Fetal globin induction--can it cure beta thalassemia? (abre una nueva ventana)

Perrine SP.

Fuente‎: Hematology Am Soc Hematol Educ Program 2005:38-44.

Indexado en‎: PubMed 16304357

DOI‎: 10.1182/asheducation-2005.1.38

https://www.ncbi.nlm.nih.gov/pubmed/16304357 (abre una nueva ventana)