Pharmacotherapy in sickle cell disease—state of the art and future prospects. (opens new window)

Hankins J, Aygun B.

Allikas‎: Br J Haematol 2009;145(3):296-308.

Indekseeritud‎: PubMed 19222472

DOI‎: 10.1111/j.1365-2141.2009.07602.x

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Long-term hydroxyurea therapy for infants with sickle cell anemia: the HUSOFT extension study. (opens new window)

Hankins JS, Ware RE, Rogers ZR, Wynn LW, Lane PA, Scott JP, Wang WC.

Allikas‎: Blood 2005;106(7):2269-75.

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DOI‎: 10.1182/Blood-2004-12-4973

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Hydroxyurea dose escalation for sickle cell anemia in sub-Saharan Africa. (opens new window)

John CC, Opoka RO, Latham TS, Hume HA, Nabaggala C, Kasirye P, Ndugwa CM, Lane A, Ware RE

Allikas‎: N Engl J Med 2020;382(26):2524-33.

Indekseeritud‎: PubMed 32579813

DOI‎: 10.1056/NEJMoa2000146

https://www.ncbi.nlm.nih.gov/pubmed/32579813 (opens new window)

The effect of hydroxcarbamide therapy on survival of children with sickle cell disease. (opens new window)

Lobo CL, Pinto JF, Nascimento EM, Moura PG, Cardoso GP, Hankins JS.

Allikas‎: Br J Haematol 2013;161(6):852-60.

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Evidence review of hydroxyurea for the prevention of sickle cell complications in low-income countries. (opens new window)

Mulaku M, Opiyo N, Karumbi J, Kitonyi G, Thoithi G, English M.

Allikas‎: Arch Dis Child 2013;98(11):908-14.

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Hydroxyurea for sickle cell disease: a systematic review for efficacy and toxicity in children. (opens new window)

Strouse JJ, Lanzkron S, Beach MC, Haywood C, Park H, Witkop C, Wilson RF, Bass EB, Segal JB.

Allikas‎: Pediatrics 2008;122(6):1332-42.

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Impact of hydroxyurea on clinical events in the BABY HUG trial. (opens new window)

Thornburg CD, Files BA, Luo Z, Miller ST, Kalpatthi R, Iyer R, Seaman P, Lebensburger J, Alvarez O, Thompson B, Ware RE, Wang WC; BABY HUG Investigators.

Allikas‎: Blood 2012;120(22):4304-10.

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Hydroxyurea for children with sickle cell anemia in sub-Saharan Africa. (opens new window)

Tshilolo L, Tomlinson G, Williams TN, Santos B, Olupot-Olupot P, Lane A, Aygun B, Stuber SE, Latham TS, McGann PT, Ware RE; REACH Investigators

Allikas‎: N Engl J Med 2019;380(2):121-31.

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Effect of hydroxyurea on growth in children with sickle cell anemia: results of the HUG-KIDS Study. (opens new window)

Wang WC, Helms RW, Lynn HS, Redding-Lallinger R, Gee BE, Ohene-Frempong K, Smith-Whitley K, Waclawiw MA, Vichinsky EP, Styles LA, Ware RE, Kinney TR.

Allikas‎: J Pediatr 2002;140(2):225-9.

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Hydroxyurea is associated with lower costs of care of young children with sickle cell anemia. (opens new window)

Wang WC, Oyeku SO, Luo Z, Boulet SL, Miller ST, Casella JF, Fish B, Thompson BW, Grosse SD; BABY HUG Investigators.

Allikas‎: Pediatrics 2013;132(4):677-83.

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Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG). (opens new window)

Wang WC, Ware RE, Miller ST, Iyer RV, Casella JF, Minniti CP, Rana S, Thornburg CD, Rogers ZR, Kalpatthi RV, Barredo JC, Brown RC, Sarnaik SA, Howard TH, Wynn LW, Kutlar A, Armstrong FD, Files BA, Goldsmith JC, Waclawiw MA, Huang X, Thompson BW; for the BABY HUG investigators.

Allikas‎: Lancet 2011;377(9778):1663-72.

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Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial. (opens new window)

Ware RE, Davis BR, Schultz WH, Brown RC, Aygun B, Sarnaik S, Odame I, Fuh B, George A, Owen W, Luchtman-Jones L, Rogers ZR, Hilliard L, Gauger C, Piccone C, Lee MT, Kwiatkowski JL, Jackson S, Miller ST, Roberts C, Heeney MM, Kalfa TA, Nelson S, Imran H, Nottage K, Alvarez O, Rhodes M, Thompson AA, Rothman JA, Helton KJ, Roberts D, Coleman J, Bonner MJ, Kutlar A, Patel N, Wood J, Piller L, Wei P, Luden J, Mortier NA, Stuber SE, Luban NL, Cohen AR, Pressel S, Adams RJ.

Allikas‎: Lancet 2016;387(10019):661-70.

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How I use hydroxyurea to treat young patients with sickle cell anemia. (opens new window)

Ware RE.

Allikas‎: Blood 2010;115(26):5300-11.

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Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease. (opens new window)

Zimmerman SA, Schultz WH, Davis JS, Pickens CV, Mortier NA, Howard TA, Ware RE.

Allikas‎: Blood 2004;103(6):2039-45.

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Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease. (opens new window)

Hirst C, Owusu-Ofori S.

Allikas‎: Cochrane Database Syst Rev 2012;(9):CD003427.

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Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial. (opens new window)

Howard J, Ataga KI, Brown RC, Achebe M, Nduba V, El-Beshlawy A, Hassab H, Agodoa I, Tonda M, Gray S, Lehrer-Graiwer J, Vichinsky E

Allikas‎: Lancet Haematol 2021;8(5):e323-33.

Indekseeritud‎: PubMed 33838113

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Sickle cell disease. (opens new window)

Meremikwu MM, Okomo U.

Allikas‎: BMJ Clin Evid 2011;02:2402.

Indekseeritud‎: PubMed 21718552

https://www.ncbi.nlm.nih.gov/pubmed/21718552 (opens new window)

A phase 3 trial of l-glutamine in sickle cell disease. (opens new window)

Niihara Y, Miller ST, Kanter J, Lanzkron S, Smith WR, Hsu LL, Gordeuk VR, Viswanathan K, Sarnaik S, Osunkwo I, Guillaume E, Sadanandan S, Sieger L, Lasky JL, Panosyan EH, Blake OA, New TN, Bellevue R, Tran LT, Razon RL, Stark CW, Neumayr LD, Vichinsky EP

Allikas‎: N Engl J Med 2018;379(3):226-35.

Indekseeritud‎: PubMed 30021096

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https://www.ncbi.nlm.nih.gov/pubmed/30021096 (opens new window)

Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa. (opens new window)

Olupot-Olupot P, Tomlinson G, Williams TN, Tshilolo L, Santos B, Smart LR, McElhinney K, Howard TA, Aygun B, Stuber SE, Lane A, Latham TS, Ware RE

Allikas‎: Blood. 2023 23;141(12):1402-10.

Indekseeritud‎: PubMed 36375125

DOI‎: 10.1182/blood.2022017051

https://pubmed.ncbi.nlm.nih.gov/36375125/ (opens new window)

Malaria chemoprophylaxis in sickle cell disease. (opens new window)

Oniyangi O, Omari AA.

Allikas‎: Cochrane Database Syst Rev 2006;(4):CD003489.

Indekseeritud‎: PubMed 17054173

DOI‎: 10.1002/14651858.CD003489.pub2

https://www.ncbi.nlm.nih.gov/pubmed/17054173 (opens new window)