Szív- és érsebészet
Hemosztázis rendezése és optimalizálása
Antifibrinolitikumok
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis. [L'application topique de médicaments anti-fibrinolytiques pour la chirurgie cardiaque avec circulation extra-corporelle : analyse méthodique et méta-analyse.] [English, French abstract] (opens new window)
Forrás: Can J Anaesth 2009;56(3):202-12.
Azonosító: PubMed 19247741
DOI: 10.1007/s12630-008-9038-x
https://www.ncbi.nlm.nih.gov/pubmed/19247741 (opens new window)
Can topical application of tranexamic acid reduce blood loss in thoracic surgery? A prospective randomised double blind investigation. (opens new window)
Forrás: Heart Lung Circ 2012;21(11):706-10.
Azonosító: PubMed 22842057
DOI: 10.1016/j.hlc.2012.06.016
https://www.ncbi.nlm.nih.gov/pubmed/22842057 (opens new window)
Can local application of tranexamic acid reduce post-coronary bypass surgery blood loss? A randomized controlled trial. (opens new window)
Forrás: J Cardiothorac Surg 2009;4:25.
Azonosító: PubMed 19538741
DOI: 10.1186/1749-8090-4-25
https://www.ncbi.nlm.nih.gov/pubmed/19538741 (opens new window)
Current status of pharmacologic therapies in patient blood management. (opens new window)
Forrás: Anesth Analg 2013;116(1):15-34.
Azonosító: PubMed 23223098
DOI: 10.1213/ANE.0b013e318273f4ae
https://www.ncbi.nlm.nih.gov/pubmed/23223098 (opens new window)
The effect of epsilon-aminocaproic acid and aprotinin on fibrinolysis and blood loss in patients undergoing primary, isolated coronary artery bypass surgery: a randomized, double-blind, placebo-controlled, noninferiority trial. (opens new window)
Forrás: Anesth Analg 2009;109(1):15-24.
Azonosító: PubMed 19535691
DOI: 10.1213/ane.0b013e3181a40b5d
https://www.ncbi.nlm.nih.gov/pubmed/19535691 (opens new window)
Putting the record straight on aprotinin as safe and effective: results from a mixed treatment meta-analysis of trials of aprotinin. (opens new window)
Forrás: J Thorac Cardiovasc Surg 2013;145(1):234-40.
Azonosító: PubMed 22889481
DOI: 10.1016/j.jtcvs.2012.07.018
https://www.ncbi.nlm.nih.gov/pubmed/22889481 (opens new window)
The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery. (opens new window)
Forrás: Anesth Analg 2010;110(1):21-9.
Azonosító: PubMed 19910626
DOI: 10.1213/ANE.0b013e3181c0ea6d
https://www.ncbi.nlm.nih.gov/pubmed/19910626 (opens new window)
Comparative evaluation of the effects of tranexamic acid and low-dose aprotinin on post-valvular heart surgery bleeding and allogenic transfusion. (opens new window)
Forrás: Interact Cardiovasc Thorac Surg 2012;15(1):23-7.
Azonosító: PubMed 22514257
DOI: 10.1093/icvts/ivs114
https://www.ncbi.nlm.nih.gov/pubmed/22514257 (opens new window)
A randomized trial of tranexamic acid in combination with cell salvage plus a meta-analysis of randomized trials evaluating tranexamic acid in off-pump coronary artery bypass grafting. (opens new window)
Forrás: J Thorac Cardiovasc Surg 2006;132(3):475-80, 480.e1-8.
Azonosító: PubMed 16935098
DOI: 10.1016/j.jtcvs.2006.01.064
https://www.ncbi.nlm.nih.gov/pubmed/16935098 (opens new window)
Tranexamic acid in patients undergoing coronary-artery surgery. (opens new window)
Forrás: N Engl J Med 2017;376(2):136-48.
Azonosító: PubMed 27774838
DOI: 10.1056/NEJMoa1606424
http://www.ncbi.nlm.nih.gov/pubmed/27774838 (opens new window)
Aprotinin for patients exposed to clopidogrel before off-pump coronary bypass. (opens new window)
Forrás: Asian Cardiovasc Thorac Ann 2008;16(6):483-7.
Azonosító: PubMed 18984759
DOI: 10.1177/021849230801600611
https://www.ncbi.nlm.nih.gov/pubmed/18984759 (opens new window)
Protective effects of tranexamic acid on clopidogrel before coronary artery bypass grafting: a multicenter randomized trial. (opens new window)
Forrás: JAMA Surg 2013;148(6):538-47.
Azonosító: PubMed 23426385
DOI: 10.1001/jamasurg.2013.1560
https://www.ncbi.nlm.nih.gov/pubmed/23426385 (opens new window)
Effect of high- vs low-dose tranexamic acid infusion on need for red blood cell transfusion and adverse events in patients undergoing cardiac surgery: The OPTIMAL randomized clinical trial. (opens new window)
Forrás: JAMA. 2022;328(4):336-47.
Azonosító: PubMed 35881121
DOI: 10.1001/jama.2022.10725
https://pubmed.ncbi.nlm.nih.gov/35881121/ (opens new window)
Tranexamic acid reduces blood loss after off-pump coronary surgery: a prospective, randomized, double-blind, placebo-controlled study. (opens new window)
Forrás: Anesth Analg 2012;115(2):239-43.
Azonosító: PubMed 21737704
DOI: 10.1213/ANE.0b013e3182264a11
https://www.ncbi.nlm.nih.gov/pubmed/21737704 (opens new window)
Effects of aprotinin on short-term and long-term outcomes after coronary artery bypass grafting surgery. (opens new window)
Forrás: Ann Thorac Surg 2010;89(5):1489-95.
Azonosító: PubMed 20417766
DOI: 10.1016/j.athoracsur.2010.02.006
https://www.ncbi.nlm.nih.gov/pubmed/20417766 (opens new window)
Low postoperative dose of aprotinin reduces bleeding and is safe in patients receiving clopidogrel before coronary artery bypass surgery. A prospective randomized study. (opens new window)
Forrás: Interact Cardiovasc Thorac Surg 2010;10(4):545-8.
Azonosító: PubMed 20067988
DOI: 10.1510/icvts.2009.226613
https://www.ncbi.nlm.nih.gov/pubmed/20067988 (opens new window)
Rekombináns aktivált VII-es faktor (rFVIIa)
Aortic dissection and hypothermic arrest in a Jehovah's Witness patient: a case for recombinant factor VIIa? (opens new window)
Forrás: Can J Anaesth 2006;53(4):353-6.
Azonosító: PubMed 16575032
DOI: 10.1007/BF03022498
https://www.ncbi.nlm.nih.gov/pubmed/16575032 (opens new window)
Use of recombinant activated factor VII for refractory after lung transplant bleeding as an effective strategy to restrict blood transfusion and associated complications. (opens new window)
Forrás: Transfusion 2013;53(4):798-804.
Azonosító: PubMed 22845023
DOI: 10.1111/j.1537-2995.2012.03801.x
https://www.ncbi.nlm.nih.gov/pubmed/22845023 (opens new window)
Recombinant activated factor VII in cardiac surgery: experience from the Australian and New Zealand Haemostasis Registry. (opens new window)
Forrás: Ann Thorac Surg 2008;85(3):836-44.
Azonosító: PubMed 18291152
DOI: 10.1016/j.athoracsur.2007.06.076
https://www.ncbi.nlm.nih.gov/pubmed/18291152 (opens new window)
Repeat cardiac surgery in a Jehovah's Witness patient with thrombocytopenia. (opens new window)
Forrás: Can J Cardiol 2011;27(6):869.e7-8.
Azonosító: PubMed 21983113
DOI: 10.1016/j.cjca.2011.07.632
https://www.ncbi.nlm.nih.gov/pubmed/21983113 (opens new window)
Off-label use of recombinant activated factor VII for cardiac surgical bleeding. (opens new window)
Forrás: Anesthesiology. 2023 1;139(2):197-210.
Azonosító: PubMed 37155359
DOI: 10.1097/ALN.0000000000004569
https://pubmed.ncbi.nlm.nih.gov/37155359/ (opens new window)
Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery. (opens new window)
Forrás: Circulation 2009;120(1):21-7.
Azonosító: PubMed 19546387
DOI: 10.1161/CIRCULATIONAHA.108.834275
https://www.ncbi.nlm.nih.gov/pubmed/19546387 (opens new window)
Intraoperative use of recombinant activated factor VII during complex aortic surgery. (opens new window)
Forrás: J Thorac Cardiovasc Surg 2012;143(5):1198-204.
Azonosító: PubMed 22285329
DOI: 10.1016/j.jtcvs.2012.01.004
https://www.ncbi.nlm.nih.gov/pubmed/22285329 (opens new window)
Off-label use of recombinant human factor VIIa. (opens new window)
Forrás: Ann Thorac Surg 2014;98(2):393-5.
Azonosító: PubMed 25087781
DOI: 10.1016/j.athoracsur.2014.06.007
https://www.ncbi.nlm.nih.gov/pubmed/25087781 (opens new window)
Off-label use of recombinant activated factor VII in intractable haemorrhage after cardiovascular surgery: an observational study of practices in 23 French cardiac centres (2005-7). (opens new window)
Forrás: Eur J Cardiothorac Surg 2011;40(6):1320-7.
Azonosító: PubMed 21550261
DOI: 10.1016/j.ejcts.2011.03.032
https://www.ncbi.nlm.nih.gov/pubmed/21550261 (opens new window)
Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery. (opens new window)
Forrás: Circulation 2008;118(4):331-8.
Azonosító: PubMed 18606914
DOI: 10.1161/CIRCULATIONAHA.108.764308
https://www.ncbi.nlm.nih.gov/pubmed/18606914 (opens new window)
Role of recombinant factor VIIa in the treatment of intractable bleeding in vascular surgery. (opens new window)
Forrás: J Vasc Surg 2011;53(4):1032-7.
Azonosító: PubMed 21215579
DOI: 10.1016/j.jvs.2010.07.075
https://www.ncbi.nlm.nih.gov/pubmed/21215579 (opens new window)
Use of activated recombinant factor VII in severe bleeding—evidence for efficacy and safety in trauma, postpartum hemorrhage, cardiac surgery, and gastrointestinal bleeding. (opens new window)
Forrás: Transfus Med Hemother 2012;39(2):139-50.
Azonosító: PubMed 22670132
DOI: 10.1159/000338034
https://www.ncbi.nlm.nih.gov/pubmed/22670132 (opens new window)
Recombinant activated factor VII for postoperative hemorrhage following repair of acute type A aortic dissection. (opens new window)
Forrás: Heart Surg Forum 2010;13(5):E275-9.
Azonosító: PubMed 20961825
DOI: 10.1532/HSF98.20101027
https://www.ncbi.nlm.nih.gov/pubmed/20961825 (opens new window)
Recombinant factor VIIa treatment of severe bleeding in cardiac surgery patients: a retrospective analysis of dosing, efficacy, and safety outcomes. (opens new window)
Forrás: J Cardiothorac Vasc Anesth 2009;23(1):28-33.
Azonosító: PubMed 18948033
DOI: 10.1053/j.jvca.2008.08.003
https://www.ncbi.nlm.nih.gov/pubmed/18948033 (opens new window)
Recombinant activated factor VII significantly reduces transfusion requirements in cardiothoracic surgery. (opens new window)
Forrás: Drugs R D 2015;15(2):187-94.
Azonosító: PubMed 25862216
DOI: 10.1007/s40268-015-0093-9
https://www.ncbi.nlm.nih.gov/pubmed/25862216 (opens new window)
Hemostatic management of severe thrombocytopenia in a patient undergoing pulmonic valve replacement. (opens new window)
Forrás: A A Case Rep 2015;5(1):3-5.
Azonosító: PubMed 26125690
DOI: 10.1213/XAA.0000000000000166
https://www.ncbi.nlm.nih.gov/pubmed/26125690 (opens new window)
Treatment of excessive bleeding in Jehovah's Witness patients after cardiac surgery with recombinant factor VIIa (Novoseven®). (opens new window)
Forrás: Anesthesiology 2003;98(6):1513-5.
Azonosító: PubMed 12766668
https://www.ncbi.nlm.nih.gov/pubmed/12766668 (opens new window)
Recombinant activated factor VII in cardiac surgery: a systematic review. (opens new window)
Forrás: Ann Thorac Surg 2007;83(2):707-14.
Azonosító: PubMed 17258029
DOI: 10.1016/j.athoracsur.2006.10.033
https://www.ncbi.nlm.nih.gov/pubmed/17258029 (opens new window)
Alvadási faktorkoncentrátumok
Reduced use of allogeneic platelets through high-yield perioperative autologous plateletpheresis and reinfusion. (opens new window)
Forrás: Transfusion 2014;54(5):1348-57.
Azonosító: PubMed 24898456
DOI: 10.1111/trf.12463
https://www.ncbi.nlm.nih.gov/pubmed/24898456 (opens new window)
Use of prothrombin complex concentrate for excessive bleeding after cardiac surgery. (opens new window)
Forrás: Interact Cardiovasc Thorac Surg 2012;15(3):382-9.
Azonosító: PubMed 22623627
DOI: 10.1093/icvts/ivs224
https://www.ncbi.nlm.nih.gov/pubmed/22623627 (opens new window)
Reducing blood transfusion in aortic surgery: a novel approach. (opens new window)
Forrás: Ann Thorac Surg 2019;108(5):1369-75.
Azonosító: PubMed 31255616
DOI: 10.1016/j.athoracsur.2019.04.127
https://www.ncbi.nlm.nih.gov/pubmed/31255616 (opens new window)
Prophylactic use of factor IX concentrate in a Jehovah's Witness patient. (opens new window)
Forrás: Ann Thorac Surg 2009;88(5):1666-8.
Azonosító: PubMed 19853132
DOI: 10.1016/j.athoracsur.2009.03.095
https://www.ncbi.nlm.nih.gov/pubmed/19853132 (opens new window)
Safety and efficacy of prothrombin complex concentrate as first-line treatment in bleeding after cardiac surgery. (opens new window)
Forrás: Crit Care 2016;20:5.
Azonosító: PubMed 26738468
DOI: 10.1186/s13054-015-1172-6
https://www.ncbi.nlm.nih.gov/pubmed/26738468 (opens new window)
Bloodless orthotopic heart transplantation in a Jehovah's Witness. (opens new window)
Forrás: A A Case Rep 2015;4(10):140-2.
Azonosító: PubMed 25974419
DOI: 10.1213/XAA.0000000000000067
https://www.ncbi.nlm.nih.gov/pubmed/25974419 (opens new window)
State of the art - how I manage coagulopathy in cardiac surgery patients. (opens new window)
Forrás: Br J Haematol 2014;164(6):779-89.
Azonosító: PubMed 24450971
DOI: 10.1111/bjh.12746
https://www.ncbi.nlm.nih.gov/pubmed/24450971 (opens new window)
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. (opens new window)
Forrás: Anesthesiology 2011;115(6):1179-91.
Azonosító: PubMed 21970887
DOI: 10.1097/ALN.0b013e31823497dd
https://www.ncbi.nlm.nih.gov/pubmed/21970887 (opens new window)
Comparison of 4-factor prothrombin complex concentrate with frozen plasma for management of hemorrhage during and after cardiac surgery: a randomized pilot trial. (opens new window)
Forrás: JAMA Netw Open 2021;4(4):e213936.
Azonosító: PubMed 33792729
DOI: 10.1001/jamanetworkopen.2021.3936
https://www.ncbi.nlm.nih.gov/pubmed/33792729 (opens new window)
Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study. (opens new window)
Forrás: Thromb Haemost 2009;102(1):137-44.
Azonosító: PubMed 19572078
DOI: 10.1160/TH08-09-0587
https://www.ncbi.nlm.nih.gov/pubmed/19572078 (opens new window)
Fibrinogen concentrate reduces intraoperative bleeding when used as first-line hemostatic therapy during major aortic replacement surgery: results from a randomized, placebo-controlled trial. (opens new window)
Forrás: J Thorac Cardiovasc Surg 2013;145(3 Suppl):S178-85.
Azonosító: PubMed 23410777
DOI: 10.1016/j.jtcvs.2012.12.083
https://www.ncbi.nlm.nih.gov/pubmed/23410777 (opens new window)
Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial. (opens new window)
Forrás: Anesthesiology 2013;118(1):40-50.
Azonosító: PubMed 23249928
DOI: 10.1097/ALN.0b013e3182715d4d
https://www.ncbi.nlm.nih.gov/pubmed/23249928 (opens new window)
Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery. (opens new window)
Forrás: J Am Heart Assoc 2015;4(6):e002066.
Azonosító: PubMed 26037084
DOI: 10.1161/JAHA.115.002066
https://www.ncbi.nlm.nih.gov/pubmed/26037084 (opens new window)
Fibrinogen supplementation after cardiac surgery: insights from the zero-plasma trial (ZEPLAST). (opens new window)
Forrás: Br J Anaesth 2016;116(5):618-23.
Azonosító: PubMed 26893405
DOI: 10.1093/bja/aev539
https://www.ncbi.nlm.nih.gov/pubmed/26893405 (opens new window)
Bleeding in a Jehovah's Witness patient undergoing a redo aortic valve replacement controlled with cryoprecipitate and a prothrombin complex concentrate. (opens new window)
Forrás: Can J Anaesth 2012;59(3):299-303.
Azonosító: PubMed 22161243
DOI: 10.1007/s12630-011-9647-7
https://www.ncbi.nlm.nih.gov/pubmed/22161243 (opens new window)
Prothrombin complex concentrate in cardiac surgery: a systematic review and meta-analysis. (opens new window)
Forrás: Ann Thorac Surg 2019;107(4):1275-83.
Azonosító: PubMed 30458156
DOI: 10.1016/j.athoracsur.2018.10.013
https://www.ncbi.nlm.nih.gov/pubmed/30458156 (opens new window)
Coagulopathy after cardiopulmonary bypass in Jehovah's Witness patients: management of two cases using fractionated components and factor VIIa. (opens new window)
Forrás: Anesth Analg 2007;104(4):763-5.
Azonosító: PubMed 17377078
DOI: 10.1213/01.ane.0000250913.45299.f3
https://www.ncbi.nlm.nih.gov/pubmed/17377078 (opens new window)
Haemostatic therapy in coronary artery bypass graft patients with decreased platelet function: comparison of fibrinogen concentrate with allogeneic blood products. (opens new window)
Forrás: Scand J Clin Lab Invest 2012;72(2):121-8.
Azonosító: PubMed 22233480
DOI: 10.3109/00365513.2011.643818
https://www.ncbi.nlm.nih.gov/pubmed/22233480 (opens new window)
Dezmopresszin
Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry. (opens new window)
Forrás: Anaesthesia 2010;65(7):688-91.
Azonosító: PubMed 20477783
DOI: 10.1111/j.1365-2044.2010.06367.x
https://www.ncbi.nlm.nih.gov/pubmed/20477783 (opens new window)
Platelet mapping and desmopressin reversal of platelet inhibition during emergency carotid endarterectomy. (opens new window)
Forrás: J Cardiothorac Vasc Anesth 2007;21(6):851-4.
Azonosító: PubMed 18068065
DOI: 10.1053/j.jvca.2007.05.009
https://www.ncbi.nlm.nih.gov/pubmed/18068065 (opens new window)
Desmopressin for reducing postoperative blood loss and transfusion requirements following cardiac surgery in adults. (opens new window)
Forrás: Interact Cardiovasc Thorac Surg 2014;18(3):360-70.
Azonosító: PubMed 24263581
DOI: 10.1093/icvts/ivt491
https://www.ncbi.nlm.nih.gov/pubmed/24263581 (opens new window)
A point-of-care assessment of the effects of desmopressin on impaired platelet function using multiple electrode whole-blood aggregometry in patients after cardiac surgery. (opens new window)
Forrás: Anesth Analg 2010;110(3):702-7.
Azonosító: PubMed 20042444
DOI: 10.1213/ANE.0b013e3181c92a5c
https://www.ncbi.nlm.nih.gov/pubmed/20042444 (opens new window)
Lokális hemosztatikumok
A comprehensive review of topical hemostatic agents: efficacy and recommendations for use. (opens new window)
Forrás: Ann Surg 2010;251(2):217-28.
Azonosító: PubMed 20010084
DOI: 10.1097/SLA.0b013e3181c3bcca
https://www.ncbi.nlm.nih.gov/pubmed/20010084 (opens new window)
A review of topical hemostatic agents for use in cardiac surgery. (opens new window)
Forrás: Ann Thorac Surg 2009;88(4):1377-83.
Azonosító: PubMed 19766855
DOI: 10.1016/j.athoracsur.2009.02.092
https://www.ncbi.nlm.nih.gov/pubmed/19766855 (opens new window)
Armentarium of topical hemostatic products in cardiovascular surgery: an update. (opens new window)
Forrás: Transfus Apher Sci 2014;50(1):26-31.
Azonosító: PubMed 24412443
DOI: 10.1016/j.transci.2013.12.009
https://www.ncbi.nlm.nih.gov/pubmed/24412443 (opens new window)
A novel reverse thermosensitive polymer to achieve temporary atraumatic vessel occlusion in infra-popliteal bypasses. (opens new window)
Forrás: Eur J Vasc Endovasc Surg 2013;45(1):51-6.
Azonosító: PubMed 23134676
DOI: 10.1016/j.ejvs.2012.10.008
https://www.ncbi.nlm.nih.gov/pubmed/23134676 (opens new window)
Drug, devices, technologies, and techniques for blood management in minimally invasive and conventional cardiothoracic surgery: a consensus statement from the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) 2011. (opens new window)
Forrás: Innovations (Phila) 2012;7(4):229-41.
Azonosító: PubMed 23123988
DOI: 10.1097/IMI.0b013e3182747699
https://www.ncbi.nlm.nih.gov/pubmed/23123988 (opens new window)
Control of troublesome bleeding during repair of acute type A dissection with use of modified rapid deployment hemostat (MRDH). (opens new window)
Forrás: J Card Surg 2009;24(6):722-4.
Azonosító: PubMed 20078720
DOI: 10.1111/j.1540-8191.2009.00915.x
https://www.ncbi.nlm.nih.gov/pubmed/20078720 (opens new window)
Topical haemostatic agents. (opens new window)
Forrás: Br J Surg 2008;95(10):1197-225.
Azonosító: PubMed 18763249
DOI: 10.1002/bjs.6357
https://www.ncbi.nlm.nih.gov/pubmed/18763249 (opens new window)
Viszkoelasztikus tesztek a sebészi vagy koagulopátiás vérzések azonosítására
An audit of red cell and blood product use after the institution of thromboelastometry in a cardiac intensive care unit. (opens new window)
Forrás: Transfus Med 2006;16(1):31-9.
Azonosító: PubMed 16480437
DOI: 10.1111/j.1365-3148.2006.00645.x
https://www.ncbi.nlm.nih.gov/pubmed/16480437 (opens new window)
First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. (opens new window)
Forrás: Anesthesiology 2011;115(6):1179-91.
Azonosító: PubMed 21970887
DOI: 10.1097/ALN.0b013e31823497dd
https://www.ncbi.nlm.nih.gov/pubmed/21970887 (opens new window)
Management of hemorrhage in cardiothoracic surgery. (opens new window)
Forrás: J Cardiothorac Vasc Anesth 2013;27(4 Suppl):S20-34.
Azonosító: PubMed 23910533
DOI: 10.1053/j.jvca.2013.05.014
https://www.ncbi.nlm.nih.gov/pubmed/23910533 (opens new window)
Point-of-care testing: a prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients. (opens new window)
Forrás: Anesthesiology 2012;117(3):531-47.
Azonosító: PubMed 22914710
DOI: 10.1097/ALN.0b013e318264c644
https://www.ncbi.nlm.nih.gov/pubmed/22914710 (opens new window)