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Chirurgia cardiotoracica e vascolare (età pediatrica)

Gestione e ottimizzazione dell’emostasi

Farmaci antifibrinolitici

Avoiding transfusions in children undergoing cardiac surgery: a meta-analysis of randomized trials of aprotinin. (apre una nuova finestra)

Arnold DM, Fergusson DA, Chan AK, Cook RJ, Fraser GA, Lim W, Blajchman MA, Cook DJ.

Fonte‎: Anesth Analg 2006;102(3):731-7.

Indicizzato‎: PubMed 16492820

DOI‎: 10.1213/01.ane.0000194954.64293.61

https://www.ncbi.nlm.nih.gov/pubmed/16492820 (apre una nuova finestra)

A systematic review of the use of antifibrinolytic agents in pediatric surgery and implications for craniofacial use. (apre una nuova finestra)

Basta MN, Stricker PA, Taylor JA.

Fonte‎: Pediatr Surg Int 2012;28(11):1059-69.

Indicizzato‎: PubMed 22940882

DOI‎: 10.1007/s00383-012-3167-6

https://www.ncbi.nlm.nih.gov/pubmed/22940882 (apre una nuova finestra)

Aprotinin, transfusions, and kidney injury in neonates and infants undergoing cardiac surgery. (apre una nuova finestra)

Bojan M, Vicca S, Boulat C, Gioanni S, Pouard P.

Fonte‎: Br J Anaesth 2012;108(5):830-7.

Indicizzato‎: PubMed 22362670

DOI‎: 10.1093/bja/aes002

https://www.ncbi.nlm.nih.gov/pubmed/22362670 (apre una nuova finestra)

Comparison of epsilon aminocaproic acid and tranexamic acid in pediatric cardiac surgery. (apre una nuova finestra)

Chauhan S, Das SN, Bisoi A, Kale S, Kiran U.

Fonte‎: J Cardiothorac Vasc Anesth 2004;18(2):141-3.

Indicizzato‎: PubMed 15073700

https://www.ncbi.nlm.nih.gov/pubmed/15073700 (apre una nuova finestra)

Efficacy of aprotinin, epsilon aminocaproic acid, or combination in cyanotic heart disease. (apre una nuova finestra)

Chauhan S, Kumar BA, Rao BH, Rao MS, Dubey B, Saxena N, Venugopal P.

Fonte‎: Ann Thorac Surg 2000;70(4):1308-12.

Indicizzato‎: PubMed 11081890

https://www.ncbi.nlm.nih.gov/pubmed/11081890 (apre una nuova finestra)

Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery. (apre una nuova finestra)

Graham EM, Atz AM, Gillis J, Desantis SM, Haney AL, Deardorff RL, Uber WE, Reeves ST, McGowan FX Jr, Bradley SM, Spinale FG.

Fonte‎: J Thorac Cardiovasc Surg 2012;143(5):1069-76.

Indicizzato‎: PubMed 22075061

DOI‎: 10.1016/j.jtcvs.2011.08.051

https://www.ncbi.nlm.nih.gov/pubmed/22075061 (apre una nuova finestra)

Intraoperative tranexamic acid in pediatric bloodless cardiac surgery. (apre una nuova finestra)

Hasegawa T, Oshima Y, Maruo A, Matsuhisa H, Tanaka A, Noda R, Yokoyama S, Iwasaki K.

Fonte‎: Asian Cardiovasc Thorac Ann 2014;22(9):1039-45.

Indicizzato‎: PubMed 24637029

DOI‎: 10.1177/0218492314527991

https://www.ncbi.nlm.nih.gov/pubmed/24637029 (apre una nuova finestra)

The safety and efficacy of antifibrinolytic therapy in neonatal cardiac surgery. (apre una nuova finestra)

Lin CY, Shuhaiber JH, Loyola H, Liu H, Del Nido P, DiNardo JA, Pigula FA.

Fonte‎: PLoS One 2015;10(5):e0126514.

Indicizzato‎: PubMed 25954976

DOI‎: 10.1371/journal.pone.0126514

https://www.ncbi.nlm.nih.gov/pubmed/25954976 (apre una nuova finestra)

Tranexamic acid versus ɛ-aminocaproic acid: efficacy and safety in paediatric cardiac surgery. (apre una nuova finestra)

Martin K, Breuer T, Gertler R, Hapfelmeier A, Schreiber C, Lange R, Hess J, Wiesner G.

Fonte‎: Eur J Cardiothorac Surg 2011;39(6):892-7.

Indicizzato‎: PubMed 21115357

DOI‎: 10.1016/j.ejcts.2010.09.041

https://www.ncbi.nlm.nih.gov/pubmed/21115357 (apre una nuova finestra)

Replacement of aprotinin by ε-aminocaproic acid in infants undergoing cardiac surgery: consequences for blood loss and outcome. (apre una nuova finestra)

Martin K, Gertler R, MacGuill M, Mayr NP, Hapfelmeier A, Hörer J, Vogt M, Tassani P, Wiesner G.

Fonte‎: Br J Anaesth 2013;110(4):615-21.

Indicizzato‎: PubMed 23213034

DOI‎: 10.1093/bja/aes430

https://www.ncbi.nlm.nih.gov/pubmed/23213034 (apre una nuova finestra)

Hematologic and economic impact of aprotinin in reoperative pediatric cardiac operations. (apre una nuova finestra)

Miller BE, Tosone SR, Tam VK, Kanter KR, Guzzetta NA, Bailey JM, Levy JH.

Fonte‎: Ann Thorac Surg 1998;66(2):535-40; discussion 541.

Indicizzato‎: PubMed 9725399

https://www.ncbi.nlm.nih.gov/pubmed/9725399 (apre una nuova finestra)

Efficacy of tranexamic acid as compared to aprotinin in open heart surgery in children. (apre una nuova finestra)

Muthialu N, Balakrishnan S, Sundar R, Muralidharan S.

Fonte‎: Ann Card Anaesth 2015;18(1):23-6.

Indicizzato‎: PubMed 25566706

DOI‎: 10.4103/0971-9784.148316

https://www.ncbi.nlm.nih.gov/pubmed/25566706 (apre una nuova finestra)

Comparative analysis of antifibrinolytic medications in pediatric heart surgery. (apre una nuova finestra)

Pasquali SK, Li JS, He X, Jacobs ML, O'Brien SM, Hall M, Jaquiss RD, Welke KF, Peterson ED, Shah SS, Jacobs JP.

Fonte‎: J Thorac Cardiovasc Surg 2012;143(3):550-7.

Indicizzato‎: PubMed 22264414

DOI‎: 10.1016/j.jtcvs.2011.06.048

https://www.ncbi.nlm.nih.gov/pubmed/22264414 (apre una nuova finestra)

Effective tranexamic acid concentration for 95% inhibition of tissue-type plasminogen activator induced hyperfibrinolysis in children with congenital heart disease: A prospective, controlled, in-vitro study. (apre una nuova finestra)

Rozen L, Faraoni D, Sanchez Torres C, Willems A, Noubouossie DC, Barglazan D, Van der Linden P, Demulder A.

Fonte‎: Eur J Anaesthesiol 2015;32(12):844-50.

Indicizzato‎: PubMed 26258658

DOI‎: 10.1097/EJA.0000000000000316

https://www.ncbi.nlm.nih.gov/pubmed/26258658 (apre una nuova finestra)

Comparison of different doses of ε-aminocaproic acid in children for tetralogy of Fallot surgery: clinical efficacy and safety. (apre una nuova finestra)

Sarupria A, Makhija N, Lakshmy R, Kiran U.

Fonte‎: J Cardiothorac Vasc Anesth 2013;27(1):23-9.

Indicizzato‎: PubMed 22995453

DOI‎: 10.1053/j.jvca.2012.07.001

https://www.ncbi.nlm.nih.gov/pubmed/22995453 (apre una nuova finestra)

Comparison of three dose regimens of aprotinin in infants undergoing the arterial switch operation. (apre una nuova finestra)

Verma YS, Chauhan S, Bisoi AK, Gharde P, Kiran U, Das SN.

Fonte‎: Ann Card Anaesth 2010;13(2):110-5.

Indicizzato‎: PubMed 20442540

DOI‎: 10.4103/0971-9784.62935

https://www.ncbi.nlm.nih.gov/pubmed/20442540 (apre una nuova finestra)

Pharmacokinetics of tranexamic acid in neonates, infants, and children undergoing cardiac surgery with cardiopulmonary bypass. (apre una nuova finestra)

Wesley MC, Pereira LM, Scharp LA, Emani SM, McGowan FX Jr, DiNardo JA.

Fonte‎: Anesthesiology 2015;122(4):746-58.

Indicizzato‎: PubMed 25585004

DOI‎: 10.1097/ALN.0000000000000570

https://www.ncbi.nlm.nih.gov/pubmed/25585004 (apre una nuova finestra)

Efficacy and safety of aprotinin in neonatal congenital heart operations. (apre una nuova finestra)

Wilder NS, Kavarana MN, Voepel-Lewis T, Paugh T, Lee T, Ohye RG.

Fonte‎: Ann Thorac Surg 2011;92(3):958-63.

Indicizzato‎: PubMed 21871283

DOI‎: 10.1016/j.athoracsur.2011.04.094

https://www.ncbi.nlm.nih.gov/pubmed/21871283 (apre una nuova finestra)

The effect of preoperative tranexamic acid on blood loss after cardiac operations in children. (apre una nuova finestra)

Zonis Z, Seear M, Reichert C, Sett S, Allen C.

Fonte‎: J Thorac Cardiovasc Surg 1996;111(5):982-7.

Indicizzato‎: PubMed 8622323

https://www.ncbi.nlm.nih.gov/pubmed/8622323 (apre una nuova finestra)

Fattore VII attivato ricombinante (rFVIIa)

Recombinant factor seven therapy for postoperative bleeding in neonatal and pediatric cardiac surgery. (apre una nuova finestra)

Agarwal HS, Bennett JE, Churchwell KB, Christian KG, Drinkwater DC Jr, He Y, Taylor MB.

Fonte‎: Ann Thorac Surg 2007;84(1):161-8.

Indicizzato‎: PubMed 17588404

DOI‎: 10.1016/j.athoracsur.2007.02.051

https://www.ncbi.nlm.nih.gov/pubmed/17588404 (apre una nuova finestra)

Pediatric off-label use of recombinant factor VIIa. (apre una nuova finestra)

Alten JA, Benner K, Green K, Toole B, Tofil NM, Winkler MK.

Fonte‎: Pediatrics 2009;123(3):1066-72.

Indicizzato‎: PubMed 19255041

DOI‎: 10.1542/peds.2008-1685

https://www.ncbi.nlm.nih.gov/pubmed/19255041 (apre una nuova finestra)

Factor VII for excessive bleeding following congenital heart disease surgery. (apre una nuova finestra)

Changlani DK, Devendaran V, Murmu UC, Ganesan S, Varghese R, Kumar RS.

Fonte‎: Asian Cardiovasc Thorac Ann 2012;20(2):120-5.

Indicizzato‎: PubMed 22499956

DOI‎: 10.1177/0218492311433614

https://www.ncbi.nlm.nih.gov/pubmed/22499956 (apre una nuova finestra)

Use of recombinant factor VIIa for uncontrolled bleeding in neonates after cardiopulmonary bypass. (apre una nuova finestra)

Guzzetta NA, Huch S, Fernandez JD, Tosone SR, Miller BE.

Fonte‎: Paediatr Anaesth 2009;19(4):364-70.

Indicizzato‎: PubMed 19143947

DOI‎: 10.1111/j.1460-9592.2008.02905.x

https://www.ncbi.nlm.nih.gov/pubmed/19143947 (apre una nuova finestra)

Review of the off-label use of recombinant activated factor VII in pediatric cardiac surgery patients. (apre una nuova finestra)

Guzzetta NA, Russell IA, Williams GD.

Fonte‎: Anesth Analg 2012;115(2):364-78.

Indicizzato‎: PubMed 22652310

DOI‎: 10.1213/ANE.0b013e31825aff10

https://www.ncbi.nlm.nih.gov/pubmed/22652310 (apre una nuova finestra)

Is recombinant activated factor VII effective in the treatment of excessive bleeding after paediatric cardiac surgery? (apre una nuova finestra)

Okonta KE, Edwin F, Falase B.

Fonte‎: Interact Cardiovasc Thorac Surg 2012;15(4):690-4.

Indicizzato‎: PubMed 22811512

DOI‎: 10.1093/icvts/ivs309

https://www.ncbi.nlm.nih.gov/pubmed/22811512 (apre una nuova finestra)

Cardiac surgery without blood products in a Jehovah's Witness child with factor VII deficiency. (apre una nuova finestra)

Pérez-Ferrer A, Gredilla E, de Vicente J, Laporta Y.

Fonte‎: J Cardiothorac Vasc Anesth 2012;26(4):651-3.

Indicizzato‎: PubMed 21924639

DOI‎: 10.1053/j.jvca.2011.07.012

https://www.ncbi.nlm.nih.gov/pubmed/21924639 (apre una nuova finestra)

Use of recombinant activated factor VII for controlling refractory postoperative bleeding in children undergoing cardiac surgery with cardiopulmonary bypass. (apre una nuova finestra)

Pychyńska-Pokorska M, Pągowska-Klimek I, Krajewski W, Moll JJ.

Fonte‎: J Cardiothorac Vasc Anesth 2011;25(6):987-94.

Indicizzato‎: PubMed 21835642

DOI‎: 10.1053/j.jvca.2011.05.012

https://www.ncbi.nlm.nih.gov/pubmed/21835642 (apre una nuova finestra)

Increased recombinant activated factor VII use and need for surgical reexploration following a switch from aprotinin to epsilon-aminocaproic acid in infant cardiac surgery. (apre una nuova finestra)

Scott JP, Costigan DJ, Hoffman GM, Simpson PM, Dasgupta M, Punzalan R, Berens RJ, Tweddell JS, Stuth EA.

Fonte‎: J Clin Anesth 2014;26(3):204-11.

Indicizzato‎: PubMed 24809789

DOI‎: 10.1016/j.jclinane.2013.10.015

https://www.ncbi.nlm.nih.gov/pubmed/24809789 (apre una nuova finestra)

Recombinant activated factor VII for hemorrhage after pediatric cardiac surgery. (apre una nuova finestra)

Singh SP, Chauhan S, Choudhary M, Vasdev S, Talwar S.

Fonte‎: Asian Cardiovasc Thorac Ann 2012;20(1):19-23.

Indicizzato‎: PubMed 22371937

DOI‎: 10.1177/0218492311432584

https://www.ncbi.nlm.nih.gov/pubmed/22371937 (apre una nuova finestra)

Recombinant factor VIIa to treat bleeding after cardiac surgery in an infant. (apre una nuova finestra)

Tobias JD, Berkenbosch JW, Russo P.

Fonte‎: Pediatr Crit Care Med 2003;4(1):49-51.

Indicizzato‎: PubMed 12656542

DOI‎: 10.1097/01.PCC.0000031472.55687.4E

https://www.ncbi.nlm.nih.gov/pubmed/12656542 (apre una nuova finestra)

Recombinant factor VIIa to control excessive bleeding following surgery for congenital heart disease in pediatric patients. (apre una nuova finestra)

Tobias JD, Simsic JM, Weinstein S, Schechter W, Kartha V, Michler R.

Fonte‎: J Intensive Care Med 2004;19(5):270-3.

Indicizzato‎: PubMed 15358945

DOI‎: 10.1177/0885066604267783

https://www.ncbi.nlm.nih.gov/pubmed/15358945 (apre una nuova finestra)

Recombinant activated factor VII in cardiac surgery: a systematic review. (apre una nuova finestra)

Warren O, Mandal K, Hadjianastassiou V, Knowlton L, Panesar S, John K, Darzi A, Athanasiou T.

Fonte‎: Ann Thorac Surg 2007;83(2):707-14.

Indicizzato‎: PubMed 17258029

DOI‎: 10.1016/j.athoracsur.2006.10.033

https://www.ncbi.nlm.nih.gov/pubmed/17258029 (apre una nuova finestra)

Defining the role of recombinant activated factor VII in pediatric cardiac surgery: where should we go from here? (apre una nuova finestra)

Warren OJ, Rogers PL, Watret AL, de Wit KL, Darzi AW, Gill R, Athanasiou T.

Fonte‎: Pediatr Crit Care Med 2009;10(5):572-82.

Indicizzato‎: PubMed 19451849

DOI‎: 10.1097/PCC.0b013e3181a642d5

https://www.ncbi.nlm.nih.gov/pubmed/19451849 (apre una nuova finestra)

Decreasing the need for transfusion: infant cardiac surgery using hemodilution and recombinant factor VIIa. (apre una nuova finestra)

Winch PD, Naguib AN, Bradshaw JR, Galantowicz M, Tobias JD.

Fonte‎: Pediatr Cardiol 2013;34(1):119-24.

Indicizzato‎: PubMed 22760694

DOI‎: 10.1007/s00246-012-0398-1

https://www.ncbi.nlm.nih.gov/pubmed/22760694 (apre una nuova finestra)

Single-center experience: use of recombinant factor VIIa for acute life-threatening bleeding in children without congenital hemorrhagic disorder. (apre una nuova finestra)

Yilmaz D, Karapinar B, Balkan C, Akisü M, Kavakli K.

Fonte‎: Pediatr Hematol Oncol 2008;25(4):301-11.

Indicizzato‎: PubMed 18484474

DOI‎: 10.1080/08880010802016904

https://www.ncbi.nlm.nih.gov/pubmed/18484474 (apre una nuova finestra)

Concentrati di fattori della coagulazione

Perioperative monitoring of thromboelastograph on blood protection and recovery for severely cyanotic patients undergoing complex cardiac surgery. (apre una nuova finestra)

Cui Y, Hei F, Long C, Feng Z, Zhao J, Yan F, Wang Y, Liu J.

Fonte‎: Artif Organs 2010;34(11):955-60.

Indicizzato‎: PubMed 21092037

DOI‎: 10.1111/j.1525-1594.2010.01148.x

https://www.ncbi.nlm.nih.gov/pubmed/21092037 (apre una nuova finestra)

Plasma fibrinogen concentration is correlated with postoperative blood loss in children undergoing cardiac surgery. A retrospective review. (apre una nuova finestra)

Faraoni D, Willems A, Savan V, Demanet H, De Ville A, Van der Linden P.

Fonte‎: Eur J Anaesthesiol 2014;31(6):317-26.

Indicizzato‎: PubMed 24503704

DOI‎: 10.1097/EJA.0000000000000043

https://www.ncbi.nlm.nih.gov/pubmed/24503704 (apre una nuova finestra)

Efficacy and safety of fibrinogen concentrate in surgical patients: a meta-analysis of randomized controlled trials. (apre una nuova finestra)

Fominskiy E, Nepomniashchikh VA, Lomivorotov VV, Monaco F, Vitiello C, Zangrillo A, Landoni G.

Fonte‎: J Cardiothorac Vasc Anesth 2016;30(5):1196-204.

Indicizzato‎: PubMed 27493092

DOI‎: 10.1053/j.jvca.2016.04.015

https://www.ncbi.nlm.nih.gov/pubmed/27493092 (apre una nuova finestra)

Hemostatic effects of fibrinogen concentrate compared with cryoprecipitate in children after cardiac surgery: a randomized pilot trial. (apre una nuova finestra)

Galas FR, de Almeida JP, Fukushima JT, Vincent JL, Osawa EA, Zeferino S, Câmara L, Guimarães VA, Jatene MB, Hajjar LA.

Fonte‎: J Thorac Cardiovasc Surg 2014;148(4):1647-55.

Indicizzato‎: PubMed 24951020

DOI‎: 10.1016/j.jtcvs.2014.04.029

https://www.ncbi.nlm.nih.gov/pubmed/24951020 (apre una nuova finestra)

Four-factor prothrombin complex concentrates in paediatric patients—a retrospective case series. (apre una nuova finestra)

Noga T, Bruce AA, Blain H, Nahirniak S.

Fonte‎: Vox Sang 2016;110(3):253-7.

Indicizzato‎: PubMed 26509839

DOI‎: 10.1111/vox.12353

https://www.ncbi.nlm.nih.gov/pubmed/26509839 (apre una nuova finestra)

Farmaci emostatici topici

A comprehensive review of topical hemostatic agents: efficacy and recommendations for use. (apre una nuova finestra)

Achneck HE, Sileshi B, Jamiolkowski RM, Albala DM, Shapiro ML, Lawson JH.

Fonte‎: Ann Surg 2010;251(2):217-28.

Indicizzato‎: PubMed 20010084

DOI‎: 10.1097/SLA.0b013e3181c3bcca

https://www.ncbi.nlm.nih.gov/pubmed/20010084 (apre una nuova finestra)

Resternotomy in pediatric cardiac surgery: CoSeal initial experience. (apre una nuova finestra)

Pace Napoleone C, Oppido G, Angeli E, Gargiulo G.

Fonte‎: Interact Cardiovasc Thorac Surg 2007;6(1):21-3.

Indicizzato‎: PubMed 17669759

DOI‎: 10.1510/icvts.2006.141531

https://www.ncbi.nlm.nih.gov/pubmed/17669759 (apre una nuova finestra)

Test viscoelastici per individuare un sanguinamento dovuto a intervento chirurgico o coagulopatia

Utility of Sonoclot analysis and tranexamic acid in tetralogy of Fallot patients undergoing intracardiac repair. (apre una nuova finestra)

Aggarwal V, Kapoor PM, Choudhury M, Kiran U, Chowdhury U.

Fonte‎: Ann Card Anaesth 2012;15(1):26-31.

Indicizzato‎: PubMed 22234018

DOI‎: 10.4103/0971-9784.91477

https://www.ncbi.nlm.nih.gov/pubmed/22234018 (apre una nuova finestra)

Perioperative monitoring of thromboelastograph on blood protection and recovery for severely cyanotic patients undergoing complex cardiac surgery. (apre una nuova finestra)

Cui Y, Hei F, Long C, Feng Z, Zhao J, Yan F, Wang Y, Liu J.

Fonte‎: Artif Organs 2010;34(11):955-60.

Indicizzato‎: PubMed 21092037

DOI‎: 10.1111/j.1525-1594.2010.01148.x

https://www.ncbi.nlm.nih.gov/pubmed/21092037 (apre una nuova finestra)

Thromboelastometry-guided intraoperative haemostatic management reduces bleeding and red cell transfusion after paediatric cardiac surgery. (apre una nuova finestra)

Nakayama Y, Nakajima Y, Tanaka KA, Sessler DI, Maeda S, Iida J, Ogawa S, Mizobe T.

Fonte‎: Br J Anaesth 2015;114(1):91-102.

Indicizzato‎: PubMed 25303988

DOI‎: 10.1093/bja/aeu339

https://www.ncbi.nlm.nih.gov/pubmed/25303988 (apre una nuova finestra)