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集中治療

止血の管理と最適化

抗線溶薬

Alternatives to allogeneic platelet transfusion. (新しいタブで開く)

Desborough MJ, Smethurst PA, Estcourt LJ, Stanworth SJ.

出典‎: Br J Haematol 2016;175(3):381-92.

インデックス‎: PubMed 27650431

DOI‎: 10.1111/bjh.14338

https://www.ncbi.nlm.nih.gov/pubmed/27650431 (新しいタブで開く)

Tranexamic acid: less bleeding and less thrombosis? (新しいタブで開く)

Godier A, Roberts I, Hunt BJ.

出典‎: Crit Care 2012;16(3):135.

インデックス‎: PubMed 22748073

DOI‎: 10.1186/cc11374

https://www.ncbi.nlm.nih.gov/pubmed/22748073 (新しいタブで開く)

Tranexamic acid for reducing mortality in emergency and urgent surgery. (新しいタブで開く)

Perel P, Ker K, Morales Uribe CH, Roberts I

出典‎: Cochrane Database Syst Rev 2013;(1):CD010245.

インデックス‎: PubMed 23440847

DOI‎: 10.1002/14651858.CD010245.pub2

https://www.ncbi.nlm.nih.gov/pubmed/23440847 (新しいタブで開く)

The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. (新しいタブで開く)

Roberts I, Shakur H, Afolabi A, Brohi K, Coats T, Dewan Y, Gando S, Guyatt G, Hunt BJ, Morales C, Perel P, Prieto-Merino D, Woolley T; CRASH-2 collaborators.

出典‎: Lancet 2011;377(9771):1096-101, 1101.e1-2.

インデックス‎: PubMed 21439633

DOI‎: 10.1016/S0140-6736(11)60278-X

https://www.ncbi.nlm.nih.gov/pubmed/21439633 (新しいタブで開く)

Antifibrinolytic drugs for acute traumatic injury. (新しいタブで開く)

Roberts I, Shakur H, Ker K, Coats T; CRASH‐2 Trial collaborators.

出典‎: Cochrane Database Syst Rev 2011;(1):CD004896.

インデックス‎: PubMed 21249666

DOI‎: 10.1002/14651858.CD004896.pub3

https://www.ncbi.nlm.nih.gov/pubmed/21249666 (新しいタブで開く)

Use of tranexamic acid to reduce bleeding in burns surgery. (新しいタブで開く)

Tang YM, Chapman TW, Brooks P

出典‎: J Plast Reconstr Aesthet Surg 2012;65(5):684-6.

インデックス‎: PubMed 21983540

DOI‎: 10.1016/j.bjps.2011.09.028

https://www.ncbi.nlm.nih.gov/pubmed/21983540 (新しいタブで開く)

Tranexamic acid reduced blood transfusions in acute burn surgery: a retrospective case-controlled trial. (新しいタブで開く)

Tapking C, Hundeshagen G, Kirchner M, Fischer S, Kneser U, Bliesener B

出典‎: Burns. 2022;48(3):522-28.

インデックス‎: PubMed 35339324

DOI‎: 10.1016/j.burns.2022.03.002

https://pubmed.ncbi.nlm.nih.gov/35339324/ (新しいタブで開く)

遺伝子組換え活性型血液凝固第Ⅶ因子製剤(rFVIIa)

Salvage use of activated recombinant factor VII in the management of refractory bleeding following cardiac surgery. (新しいタブで開く)

Barua A, Rao VP, Ramesh B, Barua B, El-Shafei H.

出典‎: J Blood Med 2011;2:131-4.

インデックス‎: PubMed 22287872

DOI‎: 10.2147/JBM.S21609

https://www.ncbi.nlm.nih.gov/pubmed/22287872 (新しいタブで開く)

The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage. (新しいタブで開く)

Boffard KD, Choong PI, Kluger Y, Riou B, Rizoli SB, Rossaint R, Warren B; NovoSeven Trauma Study Group.

出典‎: Transfusion 2009;49 Suppl 5:240S-7S.

インデックス‎: PubMed 19954486

DOI‎: 10.1111/j.1537-2995.2008.01987.x

https://www.ncbi.nlm.nih.gov/pubmed/19954486 (新しいタブで開く)

Results of the control trial: efficacy and safety of recombinant activated factor VII in the management of refractory traumatic hemorrhage. (新しいタブで開く)

Hauser CJ, Boffard K, Dutton R, Bernard GR, Croce MA, Holcomb JB, Leppaniemi A, Parr M, Vincent JL, Tortella BJ, Dimsits J, Bouillon B; CONTROL Study Group.

出典‎: J Trauma 2010;69(3):489-500.

インデックス‎: PubMed 20838118

DOI‎: 10.1097/TA.0b013e3181edf36e

https://www.ncbi.nlm.nih.gov/pubmed/20838118 (新しいタブで開く)

Use of recombinant activated factor VII in Jehovah's Witness patients with critical bleeding. (新しいタブで開く)

Kandane-Rathnayake RK, Isbister JP, Zatta AJ, Aoki NJ, Cameron P, Phillips LE; Australian and New Zealand Haemostasis Registry Steering Committee

出典‎: ANZ J Surg 2013;83(3):155-60.

インデックス‎: PubMed 23035873

DOI‎: 10.1111/j.1445-2197.2012.06285.x

https://www.ncbi.nlm.nih.gov/pubmed/23035873 (新しいタブで開く)

Recombinant factor VIIa in trauma patients with the 'triad of death.' (新しいタブで開く)

Mitra B, Cameron PA, Parr MJ, Phillips L.

出典‎: Injury 2012;43(9):1409-14.

インデックス‎: PubMed 21345431

DOI‎: 10.1016/j.injury.2011.01.033

https://www.ncbi.nlm.nih.gov/pubmed/21345431 (新しいタブで開く)

Low-dose recombinant factor VIIa for trauma patients with coagulopathy. (新しいタブで開く)

Stein DM, Dutton RP, Hess JR, Scalea TM.

出典‎: Injury 2008;39(9):1054-61.

インデックス‎: PubMed 18656871

DOI‎: 10.1016/j.injury.2008.03.032

https://www.ncbi.nlm.nih.gov/pubmed/18656871 (新しいタブで開く)

濃縮凝固因子製剤

Alternatives to allogeneic platelet transfusion. (新しいタブで開く)

Desborough MJ, Smethurst PA, Estcourt LJ, Stanworth SJ.

出典‎: Br J Haematol 2016;175(3):381-92.

インデックス‎: PubMed 27650431

DOI‎: 10.1111/bjh.14338

https://www.ncbi.nlm.nih.gov/pubmed/27650431 (新しいタブで開く)

Plasma fibrinogen level on admission to the intensive care unit is a powerful predictor of postoperative bleeding after cardiac surgery with cardiopulmonary bypass. (新しいタブで開く)

Kindo M, Hoang Minh T, Gerelli S, Perrier S, Meyer N, Schaeffer M, Bentz J, Announe T, Mommerot A, Collange O, Pottecher J, Cristinar M, Thiranos JC, Gros H, Mertes PM, Billaud P, Mazzucotelli JP

出典‎: Thromb Res 2014;134(2):360-8.

インデックス‎: PubMed 24857189

DOI‎: 10.1016/j.thromres.2014.05.008

https://www.ncbi.nlm.nih.gov/pubmed/24857189 (新しいタブで開く)

Strategies to reduce the use of blood products: a European perspective. (新しいタブで開く)

Theusinger OM, Felix C, Spahn DR.

出典‎: Curr Opin Anaesthesiol 2012;25(1):59-65.

インデックス‎: PubMed 22113184

DOI‎: 10.1097/ACO.0b013e32834dec98

https://www.ncbi.nlm.nih.gov/pubmed/22113184 (新しいタブで開く)

デスモプレシン

Desmopressin reduces transfusion needs after surgery: a meta-analysis of randomized clinical trials. (新しいタブで開く)

Crescenzi G, Landoni G, Biondi-Zoccai G, Pappalardo F, Nuzzi M, Bignami E, Fochi O, Maj G, Calabrò MG, Ranucci M, Zangrillo A

出典‎: Anesthesiology 2008;109(6):1063-76.

インデックス‎: PubMed 19034103

DOI‎: 10.1097/ALN.0b013e31818db18b

https://www.ncbi.nlm.nih.gov/pubmed/19034103 (新しいタブで開く)

Alternatives to allogeneic platelet transfusion. (新しいタブで開く)

Desborough MJ, Smethurst PA, Estcourt LJ, Stanworth SJ.

出典‎: Br J Haematol 2016;175(3):381-92.

インデックス‎: PubMed 27650431

DOI‎: 10.1111/bjh.14338

https://www.ncbi.nlm.nih.gov/pubmed/27650431 (新しいタブで開く)

Desmopressin in treatment of haematological disorders and in prevention of surgical bleeding. (新しいタブで開く)

Svensson PJ, Bergqvist PB, Juul KV, Berntorp E

出典‎: Blood Rev 2014;28(3):95-102.

インデックス‎: PubMed 24703870

DOI‎: 10.1016/j.blre.2014.03.001

https://www.ncbi.nlm.nih.gov/pubmed/24703870 (新しいタブで開く)

他の薬剤

Vitamin K deficiency and D-dimer levels in the intensive care unit: a prospective cohort study. (新しいタブで開く)

Crowther MA, McDonald E, Johnston M, Cook D

出典‎: Blood Coagul Fibrinolysis 2002;13(1):49-52.

インデックス‎: PubMed 11994567

DOI‎: 10.1097/00001721-200201000-00007

https://www.ncbi.nlm.nih.gov/pubmed/11994567 (新しいタブで開く)

局所止血剤

The use of fibrin sealant in burn operations. (新しいタブで開く)

Foster K

出典‎: Surgery 2007;142(4 Suppl):S50-4.

インデックス‎: PubMed 18019939

DOI‎: 10.1016/j.surg.2007.06.026

https://www.ncbi.nlm.nih.gov/pubmed/18019939 (新しいタブで開く)

Use of fibrin sealant in thermal injury. (新しいタブで開く)

McGill V, Kowal-Vern A, Lee M, Greenhalgh D, Gomperts E, Bray G, Gamelli R

出典‎: J Burn Care Rehabil 1997;18(5):429-34.

インデックス‎: PubMed 9313125

DOI‎: 10.1097/00004630-199709000-00011

https://www.ncbi.nlm.nih.gov/pubmed/9313125 (新しいタブで開く)

外科的出血か凝固異常による出血かを同定するための血液粘弾性試験

Perioperative treatment algorithm for bleeding burn patients reduces allogeneic blood product requirements. (新しいタブで開く)

Schaden E, Kimberger O, Kraincuk P, Baron DM, Metnitz PG, Kozek-Langenecker S

出典‎: Br J Anaesth 2012;109(3):376-81.

インデックス‎: PubMed 22719014

DOI‎: 10.1093/bja/aes186

https://www.ncbi.nlm.nih.gov/pubmed/22719014 (新しいタブで開く)

Transfusion in trauma: why and how should we change our current practice? (新しいタブで開く)

Theusinger OM, Spahn DR, Ganter MT.

出典‎: Curr Opin Anaesthesiol 2009;22(2):305-12.

インデックス‎: PubMed 19390257

DOI‎: 10.1097/ACO.0b013e3283212c7c

https://www.ncbi.nlm.nih.gov/pubmed/19390257 (新しいタブで開く)

Viscoelastic point-of-care testing to assist with the diagnosis, management and monitoring of haemostasis: a systematic review and cost-effectiveness analysis. (新しいタブで開く)

Whiting P, Al M, Westwood M, Ramos IC, Ryder S, Armstrong N, Misso K, Ross J, Severens J, Kleijnen J

出典‎: Health Technol Assess 2015;19(58):1-228.

インデックス‎: PubMed 26215747

DOI‎: 10.3310/hta19580

https://www.ncbi.nlm.nih.gov/pubmed/26215747 (新しいタブで開く)