外傷・救急医療
止血の管理と最適化
抗線溶薬
Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. (新しいタブで開く)
出典: Lancet 2019;394(10210):1713-23.
インデックス: PubMed 31623894
DOI: 10.1016/S0140-6736(19)32233-0
Alternatives to allogeneic platelet transfusion. (新しいタブで開く)
出典: Br J Haematol 2016;175(3):381-92.
インデックス: PubMed 27650431
DOI: 10.1111/bjh.14338
Antifibrinolytic drugs for acute traumatic injury. (新しいタブで開く)
出典: Cochrane Database Syst Rev 2015;(5):CD004896.
インデックス: PubMed 25956410
DOI: 10.1002/14651858.CD004896.pub4
Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study. (新しいタブで開く)
出典: JAMA Surg 2013;148(3):218-25.
インデックス: PubMed 23670117
DOI: 10.1001/jamasurg.2013.764
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. (新しいタブで開く)
出典: Lancet 2011;377(9771):1096-101, 1101.e1-2.
インデックス: PubMed 21439633
DOI: 10.1016/S0140-6736(11)60278-X
Topical tranexamic acid compared with anterior nasal packing for treatment of epistaxis in patients taking antiplatelet drugs: randomized controlled trial. (新しいタブで開く)
出典: Acad Emerg Med 2018;25(3):261-6.
インデックス: PubMed 29125679
DOI: 10.1111/acem.13345
遺伝子組換え活性型血液凝固第Ⅶ因子製剤(rFVIIa)
Efficacy of recombinant activated Factor VII in patients with massive uncontrolled bleeding: a retrospective observational analysis. (新しいタブで開く)
出典: Transfusion 2009;49(3):570-7.
インデックス: PubMed 19040498
DOI: 10.1111/j.1537-2995.2008.02001.x
The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage. (新しいタブで開く)
出典: Transfusion 2009;49 Suppl 5:240S-7S.
インデックス: PubMed 19954486
DOI: 10.1111/j.1537-2995.2008.01987.x
濃縮凝固因子製剤
The exclusive use of coagulation factor concentrates enables reversal of coagulopathy and decreases transfusion rates in patients with major blunt trauma. (新しいタブで開く)
出典: Injury 2013;44(2):209-16.
インデックス: PubMed 23000050
DOI: 10.1016/j.injury.2012.08.047
デスモプレシン
Desmopressin is a transfusion sparing option to reverse platelet dysfunction in patients with severe traumatic brain injury. (新しいタブで開く)
出典: J Trauma Acute Care Surg 2020;88(1):80-6.
インデックス: PubMed 31688782
DOI: 10.1097/TA.0000000000002521
外科的出血か凝固異常による出血かを同定するための血液粘弾性試験
Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy. (新しいタブで開く)
出典: Acta Anaesthesiol Scand 2010;54(1):111-7.
インデックス: PubMed 19860752
DOI: 10.1111/j.1399-6576.2009.02132.x
Use of rotation thromboelastometry (ROTEM) to achieve successful treatment of polytrauma with fibrinogen concentrate and prothrombin complex concentrate. (新しいタブで開く)
出典: Anaesthesia 2010;65(2):199-203.
インデックス: PubMed 19995349