Pharmacotherapy in sickle cell disease—state of the art and future prospects. (opent nieuw venster)

Hankins J, Aygun B.

Bron‎: Br J Haematol 2009;145(3):296-308.

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Long-term hydroxyurea therapy for infants with sickle cell anemia: the HUSOFT extension study. (opent nieuw venster)

Hankins JS, Ware RE, Rogers ZR, Wynn LW, Lane PA, Scott JP, Wang WC.

Bron‎: Blood 2005;106(7):2269-75.

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DOI‎: 10.1182/Blood-2004-12-4973

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Hydroxyurea dose escalation for sickle cell anemia in sub-Saharan Africa. (opent nieuw venster)

John CC, Opoka RO, Latham TS, Hume HA, Nabaggala C, Kasirye P, Ndugwa CM, Lane A, Ware RE

Bron‎: N Engl J Med 2020;382(26):2524-33.

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https://www.ncbi.nlm.nih.gov/pubmed/32579813 (opent nieuw venster)

The effect of hydroxcarbamide therapy on survival of children with sickle cell disease. (opent nieuw venster)

Lobo CL, Pinto JF, Nascimento EM, Moura PG, Cardoso GP, Hankins JS.

Bron‎: Br J Haematol 2013;161(6):852-60.

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Evidence review of hydroxyurea for the prevention of sickle cell complications in low-income countries. (opent nieuw venster)

Mulaku M, Opiyo N, Karumbi J, Kitonyi G, Thoithi G, English M.

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Hydroxyurea for sickle cell disease: a systematic review for efficacy and toxicity in children. (opent nieuw venster)

Strouse JJ, Lanzkron S, Beach MC, Haywood C, Park H, Witkop C, Wilson RF, Bass EB, Segal JB.

Bron‎: Pediatrics 2008;122(6):1332-42.

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DOI‎: 10.1542/peds.2008-0441

https://www.ncbi.nlm.nih.gov/pubmed/19047254 (opent nieuw venster)

Impact of hydroxyurea on clinical events in the BABY HUG trial. (opent nieuw venster)

Thornburg CD, Files BA, Luo Z, Miller ST, Kalpatthi R, Iyer R, Seaman P, Lebensburger J, Alvarez O, Thompson B, Ware RE, Wang WC; BABY HUG Investigators.

Bron‎: Blood 2012;120(22):4304-10.

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DOI‎: 10.1182/blood-2012-03-419879

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Hydroxyurea for children with sickle cell anemia in sub-Saharan Africa. (opent nieuw venster)

Tshilolo L, Tomlinson G, Williams TN, Santos B, Olupot-Olupot P, Lane A, Aygun B, Stuber SE, Latham TS, McGann PT, Ware RE; REACH Investigators

Bron‎: N Engl J Med 2019;380(2):121-31.

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DOI‎: 10.1056/NEJMoa1813598

https://www.ncbi.nlm.nih.gov/pubmed/30501550 (opent nieuw venster)

Effect of hydroxyurea on growth in children with sickle cell anemia: results of the HUG-KIDS Study. (opent nieuw venster)

Wang WC, Helms RW, Lynn HS, Redding-Lallinger R, Gee BE, Ohene-Frempong K, Smith-Whitley K, Waclawiw MA, Vichinsky EP, Styles LA, Ware RE, Kinney TR.

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Hydroxyurea is associated with lower costs of care of young children with sickle cell anemia. (opent nieuw venster)

Wang WC, Oyeku SO, Luo Z, Boulet SL, Miller ST, Casella JF, Fish B, Thompson BW, Grosse SD; BABY HUG Investigators.

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Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG). (opent nieuw venster)

Wang WC, Ware RE, Miller ST, Iyer RV, Casella JF, Minniti CP, Rana S, Thornburg CD, Rogers ZR, Kalpatthi RV, Barredo JC, Brown RC, Sarnaik SA, Howard TH, Wynn LW, Kutlar A, Armstrong FD, Files BA, Goldsmith JC, Waclawiw MA, Huang X, Thompson BW; for the BABY HUG investigators.

Bron‎: Lancet 2011;377(9778):1663-72.

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DOI‎: 10.1016/S0140-6736(11)60355-3

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Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial. (opent nieuw venster)

Ware RE, Davis BR, Schultz WH, Brown RC, Aygun B, Sarnaik S, Odame I, Fuh B, George A, Owen W, Luchtman-Jones L, Rogers ZR, Hilliard L, Gauger C, Piccone C, Lee MT, Kwiatkowski JL, Jackson S, Miller ST, Roberts C, Heeney MM, Kalfa TA, Nelson S, Imran H, Nottage K, Alvarez O, Rhodes M, Thompson AA, Rothman JA, Helton KJ, Roberts D, Coleman J, Bonner MJ, Kutlar A, Patel N, Wood J, Piller L, Wei P, Luden J, Mortier NA, Stuber SE, Luban NL, Cohen AR, Pressel S, Adams RJ.

Bron‎: Lancet 2016;387(10019):661-70.

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https://www.ncbi.nlm.nih.gov/pubmed/26670617 (opent nieuw venster)

How I use hydroxyurea to treat young patients with sickle cell anemia. (opent nieuw venster)

Ware RE.

Bron‎: Blood 2010;115(26):5300-11.

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DOI‎: 10.1182/blood-2009-04-146852

https://www.ncbi.nlm.nih.gov/pubmed/20223921 (opent nieuw venster)

Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease. (opent nieuw venster)

Zimmerman SA, Schultz WH, Davis JS, Pickens CV, Mortier NA, Howard TA, Ware RE.

Bron‎: Blood 2004;103(6):2039-45.

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DOI‎: 10.1182/blood-2003-07-2475

https://www.ncbi.nlm.nih.gov/pubmed/14630791 (opent nieuw venster)

Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease. (opent nieuw venster)

Hirst C, Owusu-Ofori S.

Bron‎: Cochrane Database Syst Rev 2012;(9):CD003427.

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DOI‎: 10.1002/14651858.CD003427.pub2

https://www.ncbi.nlm.nih.gov/pubmed/22972063 (opent nieuw venster)

Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial. (opent nieuw venster)

Howard J, Ataga KI, Brown RC, Achebe M, Nduba V, El-Beshlawy A, Hassab H, Agodoa I, Tonda M, Gray S, Lehrer-Graiwer J, Vichinsky E

Bron‎: Lancet Haematol 2021;8(5):e323-33.

Geïndexeerd‎: PubMed 33838113

DOI‎: 10.1016/S2352-3026(21)00059-4

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Sickle cell disease. (opent nieuw venster)

Meremikwu MM, Okomo U.

Bron‎: BMJ Clin Evid 2011;02:2402.

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https://www.ncbi.nlm.nih.gov/pubmed/21718552 (opent nieuw venster)

A phase 3 trial of l-glutamine in sickle cell disease. (opent nieuw venster)

Niihara Y, Miller ST, Kanter J, Lanzkron S, Smith WR, Hsu LL, Gordeuk VR, Viswanathan K, Sarnaik S, Osunkwo I, Guillaume E, Sadanandan S, Sieger L, Lasky JL, Panosyan EH, Blake OA, New TN, Bellevue R, Tran LT, Razon RL, Stark CW, Neumayr LD, Vichinsky EP

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Geïndexeerd‎: PubMed 30021096

DOI‎: 10.1056/NEJMoa1715971

https://www.ncbi.nlm.nih.gov/pubmed/30021096 (opent nieuw venster)

Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa. (opent nieuw venster)

Olupot-Olupot P, Tomlinson G, Williams TN, Tshilolo L, Santos B, Smart LR, McElhinney K, Howard TA, Aygun B, Stuber SE, Lane A, Latham TS, Ware RE

Bron‎: Blood. 2023 23;141(12):1402-10.

Geïndexeerd‎: PubMed 36375125

DOI‎: 10.1182/blood.2022017051

https://pubmed.ncbi.nlm.nih.gov/36375125/ (opent nieuw venster)

Malaria chemoprophylaxis in sickle cell disease. (opent nieuw venster)

Oniyangi O, Omari AA.

Bron‎: Cochrane Database Syst Rev 2006;(4):CD003489.

Geïndexeerd‎: PubMed 17054173

DOI‎: 10.1002/14651858.CD003489.pub2

https://www.ncbi.nlm.nih.gov/pubmed/17054173 (opent nieuw venster)