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Beta-Talassémia Major

Indução Farmacológica da Síntese da Hemoglobina Fetal

Hidroxiureia (Hidroxicarbamida)

Efficacy of hydroxyurea in providing transfusion independence in β-thalassemia. (abre uma nova janela)

Ansari SH, Shamsi TS, Ashraf M, Perveen K, Farzana T, Bohray M, Erum S, Mehboob T.

Fonte‎: J Pediatr Hematol Oncol 2011;33(5):339-43.

Indexado‎: PubMed 21602718

DOI‎: 10.1097/MPH.0b013e31821b0770

https://www.ncbi.nlm.nih.gov/pubmed/21602718 (abre uma nova janela)

Decreased transfusion needs associated with hydroxyurea therapy in Algerian patients with thalassemia major or intermedia. (abre uma nova janela)

Bradai M, Pissard S, Abad MT, Dechartres A, Ribeil JA, Landais P, de Montalembert M.

Fonte‎: Transfusion 2007;47(10):1830-6.

Indexado‎: PubMed 17880608

DOI‎: 10.1111/j.1537-2995.2007.01399.x

https://www.ncbi.nlm.nih.gov/pubmed/17880608 (abre uma nova janela)

Hydroxyurea increases hemoglobin F levels and improves the effectiveness of erythropoiesis in beta-thalassemia/hemoglobin E disease. (abre uma nova janela)

Fucharoen S, Siritanaratkul N, Winichagoon P, Chowthaworn J, Siriboon W, Muangsup W, Chaicharoen S, Poolsup N, Chindavijak B, Pootrakul P, Piankijagum A, Schechter AN, Rodgers GP.

Fonte‎: Blood 1996;87(3):887-92.

Indexado‎: PubMed 8562958

https://www.ncbi.nlm.nih.gov/pubmed/8562958 (abre uma nova janela)

Genotype-phenotype relationship of patients with β-thalassemia taking hydroxyurea: a 13-year experience in Iran. (abre uma nova janela)

Karimi M, Haghpanah S, Farhadi A, Yavarian M.

Fonte‎: Int J Hematol 2012;95(1):51-6.

Indexado‎: PubMed 22180324

DOI‎: 10.1007/s12185-011-0985-6

https://www.ncbi.nlm.nih.gov/pubmed/22180324 (abre uma nova janela)

Clinical experience with fetal hemoglobin induction therapy in patients with β-thalassemia. (abre uma nova janela)

Musallam KM, Taher AT, Cappellini MD, Sankaran VG.

Fonte‎: Blood 2013;121(12):2199-212.

Indexado‎: PubMed 23315167

DOI‎: 10.1182/blood-2012-10-408021

https://www.ncbi.nlm.nih.gov/pubmed/23315167 (abre uma nova janela)

A randomised double-blind placebo-controlled clinical trial of oral hydroxyurea for transfusion-dependent β-thalassaemia. (abre uma nova janela)

Yasara N, Wickramarathne N, Mettananda C, Silva I, Hameed N, Attanayaka K, Rodrigo R, Wickramasinghe N, Perera L, Manamperi A, Premawardhena A, Mettananda S

Fonte‎: Sci Rep. 2022;12(1):2752.

Indexado‎: PubMed 35177777

DOI‎: 10.1038/s41598-022-06774-8

https://pubmed.ncbi.nlm.nih.gov/35177777/ (abre uma nova janela)

Response to hydroxyurea treatment in Iranian transfusion-dependent beta-thalassemia patients. (abre uma nova janela)

Yavarian M, Karimi M, Bakker E, Harteveld CL, Giordano PC.

Fonte‎: Haematologica 2004;89(10):1172-8.

Indexado‎: PubMed 15477200

https://www.ncbi.nlm.nih.gov/pubmed/15477200 (abre uma nova janela)

Hydroxyurea therapy in 49 patients with major beta-thalassemia. (abre uma nova janela)

Zamani F, Shakeri R, Eslami SM, Razavi SM, Basi A.

Fonte‎: Arch Iran Med 2009;12(3):295-7.

Indexado‎: PubMed 19400608

https://www.ncbi.nlm.nih.gov/pubmed/19400608 (abre uma nova janela)

Eritropoetina Recombinante (Isolada ou Combinada com Outros Agentes)

Induction of fetal hemoglobin synthesis with recombinant human erythropoietin in anemic patients with heterozygous beta-thalassemia during pregnancy. (abre uma nova janela)

Breymann C, Fibach E, Visca E, Huettner C, Huch A, Huch R.

Fonte‎: J Matern Fetal Med 1999;8(1):1-7.

Indexado‎: PubMed 10052837

DOI‎: 10.1002/(SICI)1520-6661(199901/02)8:1<1::AID-MFM1>3.0.CO;2-O

https://www.ncbi.nlm.nih.gov/pubmed/10052837 (abre uma nova janela)

Treatment of beta-thalassemia patients with recombinant human erythropoietin: effect on transfusion requirements and soluble adhesion molecules. (abre uma nova janela)

Chaidos A, Makis A, Hatzimichael E, Tsiara S, Gouva M, Tzouvara E, Bourantas KL.

Fonte‎: Acta Haematol 2004;111(4):189-95.

Indexado‎: PubMed 15153710

DOI‎: 10.1159/000077551

https://www.ncbi.nlm.nih.gov/pubmed/15153710 (abre uma nova janela)

Fetal globin induction--can it cure beta thalassemia? (abre uma nova janela)

Perrine SP.

Fonte‎: Hematology Am Soc Hematol Educ Program 2005:38-44.

Indexado‎: PubMed 16304357

DOI‎: 10.1182/asheducation-2005.1.38

https://www.ncbi.nlm.nih.gov/pubmed/16304357 (abre uma nova janela)