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Cuidados Perioperatórios Pediátricos

Gestão e Otimização da Hemostase

Agentes Antifibrinolíticos

A systematic review of the use of antifibrinolytic agents in pediatric surgery and implications for craniofacial use. (abre uma nova janela)

Basta MN, Stricker PA, Taylor JA.

Fonte‎: Pediatr Surg Int 2012;28(11):1059-69.

Indexado‎: PubMed 22940882

DOI‎: 10.1007/s00383-012-3167-6

https://www.ncbi.nlm.nih.gov/pubmed/22940882 (abre uma nova janela)

Use of tranexamic acid as a rescue measure to achieve hemostasis after massive blood loss in a pediatric neurosurgical patient. (abre uma nova janela)

Bharath K, Bhagat H, Mohindra S.

Fonte‎: J Neurosurg Anesthesiol 2011;23(4):376-7.

Indexado‎: PubMed 21876453

DOI‎: 10.1097/ANA.0b013e31822c804f

https://www.ncbi.nlm.nih.gov/pubmed/21876453 (abre uma nova janela)

Aprotinin, transfusions, and kidney injury in neonates and infants undergoing cardiac surgery. (abre uma nova janela)

Bojan M, Vicca S, Boulat C, Gioanni S, Pouard P.

Fonte‎: Br J Anaesth 2012;108(5):830-7.

Indexado‎: PubMed 22362670

DOI‎: 10.1093/bja/aes002

https://www.ncbi.nlm.nih.gov/pubmed/22362670 (abre uma nova janela)

Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study. (abre uma nova janela)

Elwatidy S, Jamjoom Z, Elgamal E, Zakaria A, Turkistani A, El-Dawlatly A.

Fonte‎: Spine (Phila Pa 1976) 2008;33(24):2577-80.

Indexado‎: PubMed 19011538

DOI‎: 10.1097/BRS.0b013e318188b9c5

https://www.ncbi.nlm.nih.gov/pubmed/19011538 (abre uma nova janela)

A randomized control trial to verify the efficacy of pre-operative intravenous tranexamic acid in the control of tonsillectomy bleeding. (abre uma nova janela)

George A, Kumar R, Kumar S, Shetty S.

Fonte‎: Indian J Otolaryngol Head Neck Surg 2011;63(1):20-6.

Indexado‎: PubMed 22319712

DOI‎: 10.1007/s12070-010-0095-4

https://www.ncbi.nlm.nih.gov/pubmed/22319712 (abre uma nova janela)

Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial. (abre uma nova janela)

Goobie SM, Meier PM, Pereira LM, McGowan FX, Prescilla RP, Scharp LA, Rogers GF, Proctor MR, Meara JG, Soriano SG, Zurakowski D, Sethna NF.

Fonte‎: Anesthesiology 2011;114(4):862-71.

Indexado‎: PubMed 21364458

DOI‎: 10.1097/ALN.0b013e318210fd8f

https://www.ncbi.nlm.nih.gov/pubmed/21364458 (abre uma nova janela)

Tranexamic acid is efficacious at decreasing the rate of blood loss in adolescent scoliosis surgery: a randomized placebo-controlled trial. (abre uma nova janela)

Goobie SM, Zurakowski D, Glotzbecker MP, McCann ME, Hedequist D, Brustowicz RM, Sethna NF, Karlin LI, Emans JB, Hresko MT

Fonte‎: J Bone Joint Surg Am 2018;100(23):2024-32.

Indexado‎: PubMed 30516625

DOI‎: 10.2106/JBJS.18.00314

https://www.ncbi.nlm.nih.gov/pubmed/30516625 (abre uma nova janela)

Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery. (abre uma nova janela)

Graham EM, Atz AM, Gillis J, Desantis SM, Haney AL, Deardorff RL, Uber WE, Reeves ST, McGowan FX Jr, Bradley SM, Spinale FG.

Fonte‎: J Thorac Cardiovasc Surg 2012;143(5):1069-76.

Indexado‎: PubMed 22075061

DOI‎: 10.1016/j.jtcvs.2011.08.051

https://www.ncbi.nlm.nih.gov/pubmed/22075061 (abre uma nova janela)

Anesthetic management for transfusion-free Rastelli's procedure in a pediatric Jehovah's Witness patient. (abre uma nova janela)

Kang SH, Song I, Kang JE, Lee JH, Kim JT.

Fonte‎: Korean J Anesthesiol 2013;65(6 Suppl):S87-8.

Indexado‎: PubMed 24478887

DOI‎: 10.4097/kjae.2013.65.6S.S87

https://www.ncbi.nlm.nih.gov/pubmed/24478887 (abre uma nova janela)

The safety and efficacy of antifibrinolytic therapy in neonatal cardiac surgery. (abre uma nova janela)

Lin CY, Shuhaiber JH, Loyola H, Liu H, Del Nido P, DiNardo JA, Pigula FA.

Fonte‎: PLoS One 2015;10(5):e0126514.

Indexado‎: PubMed 25954976

DOI‎: 10.1371/journal.pone.0126514

https://www.ncbi.nlm.nih.gov/pubmed/25954976 (abre uma nova janela)

Tranexamic acid versus ɛ-aminocaproic acid: efficacy and safety in paediatric cardiac surgery. (abre uma nova janela)

Martin K, Breuer T, Gertler R, Hapfelmeier A, Schreiber C, Lange R, Hess J, Wiesner G.

Fonte‎: Eur J Cardiothorac Surg 2011;39(6):892-7.

Indexado‎: PubMed 21115357

DOI‎: 10.1016/j.ejcts.2010.09.041

https://www.ncbi.nlm.nih.gov/pubmed/21115357 (abre uma nova janela)

Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures. (abre uma nova janela)

Newton PO, Bastrom TP, Emans JB, Shah SA, Shufflebarger HL, Sponseller PD, Sucato DJ, Lenke LG.

Fonte‎: Spine (Phila Pa 1976) 2012;37(23):E1459-63.

Indexado‎: PubMed 22872217

DOI‎: 10.1097/BRS.0b013e31826c9fe4

https://www.ncbi.nlm.nih.gov/pubmed/22872217 (abre uma nova janela)

Comparative analysis of antifibrinolytic medications in pediatric heart surgery. (abre uma nova janela)

Pasquali SK, Li JS, He X, Jacobs ML, O'Brien SM, Hall M, Jaquiss RD, Welke KF, Peterson ED, Shah SS, Jacobs JP.

Fonte‎: J Thorac Cardiovasc Surg 2012;143(3):550-7.

Indexado‎: PubMed 22264414

DOI‎: 10.1016/j.jtcvs.2011.06.048

https://www.ncbi.nlm.nih.gov/pubmed/22264414 (abre uma nova janela)

Use of tranexamic acid in infants undergoing choroid plexus papilloma surgery: a report of two cases. (abre uma nova janela)

Phi JH, Goobie SM, Hong KH, Dholakia A, Smith ER.

Fonte‎: Paediatr Anaesth 2014;24(7):791-3.

Indexado‎: PubMed 24924340

DOI‎: 10.1111/pan.12447

https://www.ncbi.nlm.nih.gov/pubmed/24924340 (abre uma nova janela)

The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis. (abre uma nova janela)

Schouten ES, van de Pol AC, Schouten AN, Turner NM, Jansen NJ, Bollen CW.

Fonte‎: Pediatr Crit Care Med 2009;10(2):182-90.

Indexado‎: PubMed 19188875

DOI‎: 10.1097/PCC.0b013e3181956d61

https://www.ncbi.nlm.nih.gov/pubmed/19188875 (abre uma nova janela)

The role of Amicar in same-day anterior and posterior spinal fusion for idiopathic scoliosis. (abre uma nova janela)

Thompson GH, Florentino-Pineda I, Poe-Kochert C, Armstrong DG, Son-Hing JP.

Fonte‎: Spine (Phila Pa 1976) 2008;33(20):2237-42.

Indexado‎: PubMed 18794767

DOI‎: 10.1097/BRS.0b013e31817bd889

https://www.ncbi.nlm.nih.gov/pubmed/18794767 (abre uma nova janela)

Comparison of three dose regimens of aprotinin in infants undergoing the arterial switch operation. (abre uma nova janela)

Verma YS, Chauhan S, Bisoi AK, Gharde P, Kiran U, Das SN.

Fonte‎: Ann Card Anaesth 2010;13(2):110-5.

Indexado‎: PubMed 20442540

DOI‎: 10.4103/0971-9784.62935

https://www.ncbi.nlm.nih.gov/pubmed/20442540 (abre uma nova janela)

Pharmacokinetics of tranexamic acid in neonates, infants, and children undergoing cardiac surgery with cardiopulmonary bypass. (abre uma nova janela)

Wesley MC, Pereira LM, Scharp LA, Emani SM, McGowan FX Jr, DiNardo JA.

Fonte‎: Anesthesiology 2015;122(4):746-58.

Indexado‎: PubMed 25585004

DOI‎: 10.1097/ALN.0000000000000570

https://www.ncbi.nlm.nih.gov/pubmed/25585004 (abre uma nova janela)

Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis? (abre uma nova janela)

Yagi M, Hasegawa J, Nagoshi N, Iizuka S, Kaneko S, Fukuda K, Takemitsu M, Shioda M, Machida M.

Fonte‎: Spine (Phila Pa 1976) 2012;37(21):E1336-42.

Indexado‎: PubMed 22772572

DOI‎: 10.1097/BRS.0b013e318266b6e5

https://www.ncbi.nlm.nih.gov/pubmed/22772572 (abre uma nova janela)

Fator VII Recombinante Ativado (rFVIIa)

Pediatric off-label use of recombinant factor VIIa. (abre uma nova janela)

Alten JA, Benner K, Green K, Toole B, Tofil NM, Winkler MK.

Fonte‎: Pediatrics 2009;123(3):1066-72.

Indexado‎: PubMed 19255041

DOI‎: 10.1542/peds.2008-1685

https://www.ncbi.nlm.nih.gov/pubmed/19255041 (abre uma nova janela)

Recombinant activated factor VII usage in life threatening hemorrhage: a pediatric experience. (abre uma nova janela)

Bhat S, Yadav SP, Anjan M, Dinand V, Sachdeva A.

Fonte‎: Indian J Pediatr 2011;78(8):961-8.

Indexado‎: PubMed 21328080

DOI‎: 10.1007/s12098-011-0364-6

https://www.ncbi.nlm.nih.gov/pubmed/21328080 (abre uma nova janela)

Recombinant activated factor VII (rFVIIa) treatment in infants with hemorrhage. (abre uma nova janela)

Brady KM, Easley RB, Tobias JD.

Fonte‎: Paediatr Anaesth 2006;16(10):1042-6.

Indexado‎: PubMed 16972833

DOI‎: 10.1111/j.1460-9592.2006.02039.x

https://www.ncbi.nlm.nih.gov/pubmed/16972833 (abre uma nova janela)

Review of the off-label use of recombinant activated factor VII in pediatric cardiac surgery patients. (abre uma nova janela)

Guzzetta NA, Russell IA, Williams GD.

Fonte‎: Anesth Analg 2012;115(2):364-78.

Indexado‎: PubMed 22652310

DOI‎: 10.1213/ANE.0b013e31825aff10

https://www.ncbi.nlm.nih.gov/pubmed/22652310 (abre uma nova janela)

Use of recombinant activated factor VII for controlling refractory postoperative bleeding in children undergoing cardiac surgery with cardiopulmonary bypass. (abre uma nova janela)

Pychyńska-Pokorska M, Pągowska-Klimek I, Krajewski W, Moll JJ.

Fonte‎: J Cardiothorac Vasc Anesth 2011;25(6):987-94.

Indexado‎: PubMed 21835642

DOI‎: 10.1053/j.jvca.2011.05.012

https://www.ncbi.nlm.nih.gov/pubmed/21835642 (abre uma nova janela)

Recombinant activated factor VII for hemorrhage after pediatric cardiac surgery. (abre uma nova janela)

Singh SP, Chauhan S, Choudhary M, Vasdev S, Talwar S.

Fonte‎: Asian Cardiovasc Thorac Ann 2012;20(1):19-23.

Indexado‎: PubMed 22371937

DOI‎: 10.1177/0218492311432584

https://www.ncbi.nlm.nih.gov/pubmed/22371937 (abre uma nova janela)

Single-center experience: use of recombinant factor VIIa for acute life-threatening bleeding in children without congenital hemorrhagic disorder. (abre uma nova janela)

Yilmaz D, Karapinar B, Balkan C, Akisü M, Kavakli K.

Fonte‎: Pediatr Hematol Oncol 2008;25(4):301-11.

Indexado‎: PubMed 18484474

DOI‎: 10.1080/08880010802016904

https://www.ncbi.nlm.nih.gov/pubmed/18484474 (abre uma nova janela)

Off-label use of rFVIIa in children with excessive bleeding: a consecutive study of 153 off-label uses in 139 children. (abre uma nova janela)

Young G, Wicklund B, Neff P, Johnson C, Nugent DJ.

Fonte‎: Pediatr Blood Cancer 2009;53(2):179-83.

Indexado‎: PubMed 19415741

DOI‎: 10.1002/pbc.22053

https://www.ncbi.nlm.nih.gov/pubmed/19415741 (abre uma nova janela)

Concentrados de Fatores de Coagulação

Emergent pediatric anticoagulation reversal using a 4-factor prothrombin complex concentrate. (abre uma nova janela)

Adams CB, Vollman KE, Leventhal EL, Acquisto NM.

Fonte‎: Am J Emerg Med 2016;34(6):1182.e1-2.

Indexado‎: PubMed 26652577

DOI‎: 10.1016/j.ajem.2015.10.041

https://www.ncbi.nlm.nih.gov/pubmed/26652577 (abre uma nova janela)

Perioperative monitoring of thromboelastograph on blood protection and recovery for severely cyanotic patients undergoing complex cardiac surgery. (abre uma nova janela)

Cui Y, Hei F, Long C, Feng Z, Zhao J, Yan F, Wang Y, Liu J.

Fonte‎: Artif Organs 2010;34(11):955-60.

Indexado‎: PubMed 21092037

DOI‎: 10.1111/j.1525-1594.2010.01148.x

https://www.ncbi.nlm.nih.gov/pubmed/21092037 (abre uma nova janela)

Plasma fibrinogen concentration is correlated with postoperative blood loss in children undergoing cardiac surgery. A retrospective review. (abre uma nova janela)

Faraoni D, Willems A, Savan V, Demanet H, De Ville A, Van der Linden P.

Fonte‎: Eur J Anaesthesiol 2014;31(6):317-26.

Indexado‎: PubMed 24503704

DOI‎: 10.1097/EJA.0000000000000043

https://www.ncbi.nlm.nih.gov/pubmed/24503704 (abre uma nova janela)

Hemostatic effects of fibrinogen concentrate compared with cryoprecipitate in children after cardiac surgery: a randomized pilot trial. (abre uma nova janela)

Galas FR, de Almeida JP, Fukushima JT, Vincent JL, Osawa EA, Zeferino S, Câmara L, Guimarães VA, Jatene MB, Hajjar LA.

Fonte‎: J Thorac Cardiovasc Surg 2014;148(4):1647-55.

Indexado‎: PubMed 24951020

DOI‎: 10.1016/j.jtcvs.2014.04.029

https://www.ncbi.nlm.nih.gov/pubmed/24951020 (abre uma nova janela)

Four-factor prothrombin complex concentrates in paediatric patients—a retrospective case series. (abre uma nova janela)

Noga T, Bruce AA, Blain H, Nahirniak S.

Fonte‎: Vox Sang 2016;110(3):253-7.

Indexado‎: PubMed 26509839

DOI‎: 10.1111/vox.12353

https://www.ncbi.nlm.nih.gov/pubmed/26509839 (abre uma nova janela)

Testes Viscoelásticos para Identificar Hemorragia Cirúrgica ou Coagulopatia

Utility of Sonoclot analysis and tranexamic acid in tetralogy of Fallot patients undergoing intracardiac repair. (abre uma nova janela)

Aggarwal V, Kapoor PM, Choudhury M, Kiran U, Chowdhury U.

Fonte‎: Ann Card Anaesth 2012;15(1):26-31.

Indexado‎: PubMed 22234018

DOI‎: 10.4103/0971-9784.91477

https://www.ncbi.nlm.nih.gov/pubmed/22234018 (abre uma nova janela)

Perioperative bleeding management in pediatric patients. (abre uma nova janela)

Goobie SM, Haas T.

Fonte‎: Curr Opin Anaesthesiol 2016;29(3):352-8.

Indexado‎: PubMed 26844864

DOI‎: 10.1097/ACO.0000000000000308

https://www.ncbi.nlm.nih.gov/pubmed/26844864 (abre uma nova janela)

Management of dilutional coagulopathy during pediatric major surgery. (abre uma nova janela)

Haas T, Mauch J, Weiss M, Schmugge M.

Fonte‎: Transfus Med Hemother 2012;39(2):114-9.

Indexado‎: PubMed 22670129

DOI‎: 10.1159/000337245

https://www.ncbi.nlm.nih.gov/pubmed/22670129 (abre uma nova janela)

Higher fibrinogen concentrations for reduction of transfusion requirements during major paediatric surgery: a prospective randomised controlled trial. (abre uma nova janela)

Haas T, Spielmann N, Restin T, Seifert B, Henze G, Obwegeser J, Min K, Jeszenszky D, Weiss M, Schmugge M.

Fonte‎: Br J Anaesth 2015;115(2):234-43.

Indexado‎: PubMed 25982134

DOI‎: 10.1093/bja/aev136

https://www.ncbi.nlm.nih.gov/pubmed/25982134 (abre uma nova janela)

Thromboelastometry-guided intraoperative haemostatic management reduces bleeding and red cell transfusion after paediatric cardiac surgery. (abre uma nova janela)

Nakayama Y, Nakajima Y, Tanaka KA, Sessler DI, Maeda S, Iida J, Ogawa S, Mizobe T.

Fonte‎: Br J Anaesth 2015;114(1):91-102.

Indexado‎: PubMed 25303988

DOI‎: 10.1093/bja/aeu339

https://www.ncbi.nlm.nih.gov/pubmed/25303988 (abre uma nova janela)

Cardiac surgery without blood products in a Jehovah's Witness child with factor VII deficiency. (abre uma nova janela)

Pérez-Ferrer A, Gredilla E, de Vicente J, Laporta Y.

Fonte‎: J Cardiothorac Vasc Anesth 2012;26(4):651-3.

Indexado‎: PubMed 21924639

DOI‎: 10.1053/j.jvca.2011.07.012

https://www.ncbi.nlm.nih.gov/pubmed/21924639 (abre uma nova janela)