Pular para conteúdo

Trauma e medicina de urgência

Manejo e otimização da hemostasia

Antifibrinolíticos 

Alternatives to allogeneic platelet transfusion. (abre nova janela)

Desborough MJ, Smethurst PA, Estcourt LJ, Stanworth SJ.

Fonte‎: Br J Haematol 2016;175(3):381-92.

Indexado‎: PubMed 27650431

DOI‎: 10.1111/bjh.14338

https://www.ncbi.nlm.nih.gov/pubmed/27650431 (abre nova janela)

Antifibrinolytic drugs for acute traumatic injury. (abre nova janela)

Ker K, Roberts I, Shakur H, Coats TJ.

Fonte‎: Cochrane Database Syst Rev 2015;(5):CD004896.

Indexado‎: PubMed 25956410

DOI‎: 10.1002/14651858.CD004896.pub4

https://www.ncbi.nlm.nih.gov/pubmed/25956410 (abre nova janela)

Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study. (abre nova janela)

Morrison JJ, Ross JD, Dubose JJ, Jansen JO, Midwinter MJ, Rasmussen TE.

Fonte‎: JAMA Surg 2013;148(3):218-25.

Indexado‎: PubMed 23670117

DOI‎: 10.1001/jamasurg.2013.764

https://www.ncbi.nlm.nih.gov/pubmed/23670117 (abre nova janela)

The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. (abre nova janela)

Roberts I, Shakur H, Afolabi A, Brohi K, Coats T, Dewan Y, Gando S, Guyatt G, Hunt BJ, Morales C, Perel P, Prieto-Merino D, Woolley T; CRASH-2 collaborators.

Fonte‎: Lancet 2011;377(9771):1096-101, 1101.e1-2.

Indexado‎: PubMed 21439633

DOI‎: 10.1016/S0140-6736(11)60278-X

https://www.ncbi.nlm.nih.gov/pubmed/21439633 (abre nova janela)

Fator VII recombinante ativado (rFVIIa)

The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage. (abre nova janela)

Boffard KD, Choong PI, Kluger Y, Riou B, Rizoli SB, Rossaint R, Warren B; NovoSeven Trauma Study Group.

Fonte‎: Transfusion 2009;49 Suppl 5:240S-7S.

Indexado‎: PubMed 19954486

DOI‎: 10.1111/j.1537-2995.2008.01987.x

https://www.ncbi.nlm.nih.gov/pubmed/19954486 (abre nova janela)

Concentrados de fatores de coagulação 

The exclusive use of coagulation factor concentrates enables reversal of coagulopathy and decreases transfusion rates in patients with major blunt trauma. (abre nova janela)

Innerhofer P, Westermann I, Tauber H, Breitkopf R, Fries D, Kastenberger T, El Attal R, Strasak A, Mittermayr M.

Fonte‎: Injury 2013;44(2):209-16.

Indexado‎: PubMed 23000050

DOI‎: 10.1016/j.injury.2012.08.047

https://www.ncbi.nlm.nih.gov/pubmed/23000050 (abre nova janela)

Desmopressina 

Desmopressin is a transfusion sparing option to reverse platelet dysfunction in patients with severe traumatic brain injury. (abre nova janela)

Furay EJ, Daley MJ, Satarasinghe P, Lara S, Aydelotte JD, Teixeira PG, Coopwood TB, Ali S, Brown CVR

Fonte‎: J Trauma Acute Care Surg 2020;88(1):80-6.

Indexado‎: PubMed 31688782

DOI‎: 10.1097/TA.0000000000002521

https://www.ncbi.nlm.nih.gov/pubmed/31688782 (abre nova janela)

Testes viscoelásticos para identificar sangramento cirúrgico ou coagulopático

Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy. (abre nova janela)

Brenni M, Worn M, Brüesch M, Spahn DR, Ganter MT.

Fonte‎: Acta Anaesthesiol Scand 2010;54(1):111-7.

Indexado‎: PubMed 19860752

DOI‎: 10.1111/j.1399-6576.2009.02132.x

https://www.ncbi.nlm.nih.gov/pubmed/19860752 (abre nova janela)