Trauma e medicina de urgência
Manejo e otimização da hemostasia
Antifibrinolíticos
Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. (abre nova janela)
Fonte: Lancet 2019;394(10210):1713-23.
Indexado: PubMed 31623894
DOI: 10.1016/S0140-6736(19)32233-0
https://www.ncbi.nlm.nih.gov/pubmed/31623894 (abre nova janela)
Alternatives to allogeneic platelet transfusion. (abre nova janela)
Fonte: Br J Haematol 2016;175(3):381-92.
Indexado: PubMed 27650431
DOI: 10.1111/bjh.14338
https://www.ncbi.nlm.nih.gov/pubmed/27650431 (abre nova janela)
Antifibrinolytic drugs for acute traumatic injury. (abre nova janela)
Fonte: Cochrane Database Syst Rev 2015;(5):CD004896.
Indexado: PubMed 25956410
DOI: 10.1002/14651858.CD004896.pub4
https://www.ncbi.nlm.nih.gov/pubmed/25956410 (abre nova janela)
Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study. (abre nova janela)
Fonte: JAMA Surg 2013;148(3):218-25.
Indexado: PubMed 23670117
DOI: 10.1001/jamasurg.2013.764
https://www.ncbi.nlm.nih.gov/pubmed/23670117 (abre nova janela)
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. (abre nova janela)
Fonte: Lancet 2011;377(9771):1096-101, 1101.e1-2.
Indexado: PubMed 21439633
DOI: 10.1016/S0140-6736(11)60278-X
https://www.ncbi.nlm.nih.gov/pubmed/21439633 (abre nova janela)
Topical tranexamic acid compared with anterior nasal packing for treatment of epistaxis in patients taking antiplatelet drugs: randomized controlled trial. (abre nova janela)
Fonte: Acad Emerg Med 2018;25(3):261-6.
Indexado: PubMed 29125679
DOI: 10.1111/acem.13345
https://www.ncbi.nlm.nih.gov/pubmed/29125679 (abre nova janela)
Fator VII recombinante ativado (rFVIIa)
Efficacy of recombinant activated Factor VII in patients with massive uncontrolled bleeding: a retrospective observational analysis. (abre nova janela)
Fonte: Transfusion 2009;49(3):570-7.
Indexado: PubMed 19040498
DOI: 10.1111/j.1537-2995.2008.02001.x
https://www.ncbi.nlm.nih.gov/pubmed/19040498 (abre nova janela)
The treatment of bleeding is to stop the bleeding! Treatment of trauma-related hemorrhage. (abre nova janela)
Fonte: Transfusion 2009;49 Suppl 5:240S-7S.
Indexado: PubMed 19954486
DOI: 10.1111/j.1537-2995.2008.01987.x
https://www.ncbi.nlm.nih.gov/pubmed/19954486 (abre nova janela)
Concentrados de fatores de coagulação
The exclusive use of coagulation factor concentrates enables reversal of coagulopathy and decreases transfusion rates in patients with major blunt trauma. (abre nova janela)
Fonte: Injury 2013;44(2):209-16.
Indexado: PubMed 23000050
DOI: 10.1016/j.injury.2012.08.047
https://www.ncbi.nlm.nih.gov/pubmed/23000050 (abre nova janela)
Desmopressina
Desmopressin is a transfusion sparing option to reverse platelet dysfunction in patients with severe traumatic brain injury. (abre nova janela)
Fonte: J Trauma Acute Care Surg 2020;88(1):80-6.
Indexado: PubMed 31688782
DOI: 10.1097/TA.0000000000002521
https://www.ncbi.nlm.nih.gov/pubmed/31688782 (abre nova janela)
Testes viscoelásticos para identificar sangramento cirúrgico ou coagulopático
Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy. (abre nova janela)
Fonte: Acta Anaesthesiol Scand 2010;54(1):111-7.
Indexado: PubMed 19860752
DOI: 10.1111/j.1399-6576.2009.02132.x
https://www.ncbi.nlm.nih.gov/pubmed/19860752 (abre nova janela)
Use of rotation thromboelastometry (ROTEM) to achieve successful treatment of polytrauma with fibrinogen concentrate and prothrombin complex concentrate. (abre nova janela)
Fonte: Anaesthesia 2010;65(2):199-203.
Indexado: PubMed 19995349
https://www.ncbi.nlm.nih.gov/pubmed/19995349 (abre nova janela)