Doença falciforme
Prevenção de crises
Indução farmacológica da hemoglobina fetal
Systematic review: hydroxyurea for the treatment of adults with sickle cell disease. (abre nova janela)
Fonte: Ann Intern Med 2008;148(12):939-55.
Indexado: PubMed 18458272
https://www.ncbi.nlm.nih.gov/pubmed/18458272 (abre nova janela)
Cost-effectiveness of hydroxyurea in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia. (abre nova janela)
Fonte: Am J Hematol 2000;64(1):26-31.
Indexado: PubMed 10815784
https://www.ncbi.nlm.nih.gov/pubmed/10815784 (abre nova janela)
Hydroxyurea for the treatment of sickle cell anemia. (abre nova janela)
Fonte: N Engl J Med 2008;358(13):1362-9.
Indexado: PubMed 18367739
DOI: 10.1056/NEJMct0708272
https://www.ncbi.nlm.nih.gov/pubmed/18367739 (abre nova janela)
Clinical effectiveness of decitabine in severe sickle cell disease. (abre nova janela)
Fonte: Br J Haematol 2008;141(1):126-9.
Indexado: PubMed 18324975
DOI: 10.1111/j.1365-2141.2008.07027.x
https://www.ncbi.nlm.nih.gov/pubmed/18324975 (abre nova janela)
The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS). (abre nova janela)
Fonte: Blood 2010;115(12):2354-63.
Indexado: PubMed 19903897
DOI: 10.1182/blood-2009-05-221333
https://www.ncbi.nlm.nih.gov/pubmed/19903897 (abre nova janela)
Prevenção de infecções e outras complicações
Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease. (abre nova janela)
Fonte: Cochrane Database Syst Rev 2012;(9):CD003427.
Indexado: PubMed 22972063
DOI: 10.1002/14651858.CD003427.pub2
https://www.ncbi.nlm.nih.gov/pubmed/22972063 (abre nova janela)
Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial. (abre nova janela)
Fonte: Lancet Haematol 2021;8(5):e323-33.
Indexado: PubMed 33838113
DOI: 10.1016/S2352-3026(21)00059-4
https://www.ncbi.nlm.nih.gov/pubmed/33838113 (abre nova janela)
Sickle cell disease. (abre nova janela)
Fonte: BMJ Clin Evid 2011;02:2402.
Indexado: PubMed 21718552
https://www.ncbi.nlm.nih.gov/pubmed/21718552 (abre nova janela)
A phase 3 trial of l-glutamine in sickle cell disease. (abre nova janela)
Fonte: N Engl J Med 2018;379(3):226-35.
Indexado: PubMed 30021096
DOI: 10.1056/NEJMoa1715971
https://www.ncbi.nlm.nih.gov/pubmed/30021096 (abre nova janela)
Malaria chemoprophylaxis in sickle cell disease. (abre nova janela)
Fonte: Cochrane Database Syst Rev 2006;(4):CD003489.
Indexado: PubMed 17054173
DOI: 10.1002/14651858.CD003489.pub2
https://www.ncbi.nlm.nih.gov/pubmed/17054173 (abre nova janela)