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Orak Hücre Hastalığı (Çocuk)

Krizin Önlenmesi

Farmakolojik Ajanlarla (ilaçlarla) Fetal Hemoglobin Sentezi

Pharmacotherapy in sickle cell disease—state of the art and future prospects. (yeni pencere açar)

Hankins J, Aygun B.

Kaynak‎: Br J Haematol 2009;145(3):296-308.

İndeks‎: PubMed 19222472

DOI‎: 10.1111/j.1365-2141.2009.07602.x

https://www.ncbi.nlm.nih.gov/pubmed/19222472 (yeni pencere açar)

Long-term hydroxyurea therapy for infants with sickle cell anemia: the HUSOFT extension study. (yeni pencere açar)

Hankins JS, Ware RE, Rogers ZR, Wynn LW, Lane PA, Scott JP, Wang WC.

Kaynak‎: Blood 2005;106(7):2269-75.

İndeks‎: PubMed 16172253

DOI‎: 10.1182/Blood-2004-12-4973

https://www.ncbi.nlm.nih.gov/pubmed/16172253 (yeni pencere açar)

Hydroxyurea dose escalation for sickle cell anemia in sub-Saharan Africa. (yeni pencere açar)

John CC, Opoka RO, Latham TS, Hume HA, Nabaggala C, Kasirye P, Ndugwa CM, Lane A, Ware RE

Kaynak‎: N Engl J Med 2020;382(26):2524-33.

İndeks‎: PubMed 32579813

DOI‎: 10.1056/NEJMoa2000146

https://www.ncbi.nlm.nih.gov/pubmed/32579813 (yeni pencere açar)

The effect of hydroxcarbamide therapy on survival of children with sickle cell disease. (yeni pencere açar)

Lobo CL, Pinto JF, Nascimento EM, Moura PG, Cardoso GP, Hankins JS.

Kaynak‎: Br J Haematol 2013;161(6):852-60.

İndeks‎: PubMed 23590693

DOI‎: 10.1111/bjh.12323

https://www.ncbi.nlm.nih.gov/pubmed/23590693 (yeni pencere açar)

Evidence review of hydroxyurea for the prevention of sickle cell complications in low-income countries. (yeni pencere açar)

Mulaku M, Opiyo N, Karumbi J, Kitonyi G, Thoithi G, English M.

Kaynak‎: Arch Dis Child 2013;98(11):908-14.

İndeks‎: PubMed 23995076

DOI‎: 10.1136/archdischild-2012-302387

https://www.ncbi.nlm.nih.gov/pubmed/23995076 (yeni pencere açar)

Hydroxyurea for sickle cell disease: a systematic review for efficacy and toxicity in children. (yeni pencere açar)

Strouse JJ, Lanzkron S, Beach MC, Haywood C, Park H, Witkop C, Wilson RF, Bass EB, Segal JB.

Kaynak‎: Pediatrics 2008;122(6):1332-42.

İndeks‎: PubMed 19047254

DOI‎: 10.1542/peds.2008-0441

https://www.ncbi.nlm.nih.gov/pubmed/19047254 (yeni pencere açar)

Impact of hydroxyurea on clinical events in the BABY HUG trial. (yeni pencere açar)

Thornburg CD, Files BA, Luo Z, Miller ST, Kalpatthi R, Iyer R, Seaman P, Lebensburger J, Alvarez O, Thompson B, Ware RE, Wang WC; BABY HUG Investigators.

Kaynak‎: Blood 2012;120(22):4304-10.

İndeks‎: PubMed 22915643

DOI‎: 10.1182/blood-2012-03-419879

https://www.ncbi.nlm.nih.gov/pubmed/22915643 (yeni pencere açar)

Hydroxyurea for children with sickle cell anemia in sub-Saharan Africa. (yeni pencere açar)

Tshilolo L, Tomlinson G, Williams TN, Santos B, Olupot-Olupot P, Lane A, Aygun B, Stuber SE, Latham TS, McGann PT, Ware RE; REACH Investigators

Kaynak‎: N Engl J Med 2019;380(2):121-31.

İndeks‎: PubMed 30501550

DOI‎: 10.1056/NEJMoa1813598

https://www.ncbi.nlm.nih.gov/pubmed/30501550 (yeni pencere açar)

Effect of hydroxyurea on growth in children with sickle cell anemia: results of the HUG-KIDS Study. (yeni pencere açar)

Wang WC, Helms RW, Lynn HS, Redding-Lallinger R, Gee BE, Ohene-Frempong K, Smith-Whitley K, Waclawiw MA, Vichinsky EP, Styles LA, Ware RE, Kinney TR.

Kaynak‎: J Pediatr 2002;140(2):225-9.

İndeks‎: PubMed 11865275

DOI‎: 10.1067/mpd.2002.121383

https://www.ncbi.nlm.nih.gov/pubmed/11865275 (yeni pencere açar)

Hydroxyurea is associated with lower costs of care of young children with sickle cell anemia. (yeni pencere açar)

Wang WC, Oyeku SO, Luo Z, Boulet SL, Miller ST, Casella JF, Fish B, Thompson BW, Grosse SD; BABY HUG Investigators.

Kaynak‎: Pediatrics 2013;132(4):677-83.

İndeks‎: PubMed 23999955

DOI‎: 10.1542/peds.2013-0333

https://www.ncbi.nlm.nih.gov/pubmed/23999955 (yeni pencere açar)

Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG). (yeni pencere açar)

Wang WC, Ware RE, Miller ST, Iyer RV, Casella JF, Minniti CP, Rana S, Thornburg CD, Rogers ZR, Kalpatthi RV, Barredo JC, Brown RC, Sarnaik SA, Howard TH, Wynn LW, Kutlar A, Armstrong FD, Files BA, Goldsmith JC, Waclawiw MA, Huang X, Thompson BW; for the BABY HUG investigators.

Kaynak‎: Lancet 2011;377(9778):1663-72.

İndeks‎: PubMed 21571150

DOI‎: 10.1016/S0140-6736(11)60355-3

https://www.ncbi.nlm.nih.gov/pubmed/21571150 (yeni pencere açar)

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial. (yeni pencere açar)

Ware RE, Davis BR, Schultz WH, Brown RC, Aygun B, Sarnaik S, Odame I, Fuh B, George A, Owen W, Luchtman-Jones L, Rogers ZR, Hilliard L, Gauger C, Piccone C, Lee MT, Kwiatkowski JL, Jackson S, Miller ST, Roberts C, Heeney MM, Kalfa TA, Nelson S, Imran H, Nottage K, Alvarez O, Rhodes M, Thompson AA, Rothman JA, Helton KJ, Roberts D, Coleman J, Bonner MJ, Kutlar A, Patel N, Wood J, Piller L, Wei P, Luden J, Mortier NA, Stuber SE, Luban NL, Cohen AR, Pressel S, Adams RJ.

Kaynak‎: Lancet 2016;387(10019):661-70.

İndeks‎: PubMed 26670617

https://www.ncbi.nlm.nih.gov/pubmed/26670617 (yeni pencere açar)

How I use hydroxyurea to treat young patients with sickle cell anemia. (yeni pencere açar)

Ware RE.

Kaynak‎: Blood 2010;115(26):5300-11.

İndeks‎: PubMed 20223921

DOI‎: 10.1182/blood-2009-04-146852

https://www.ncbi.nlm.nih.gov/pubmed/20223921 (yeni pencere açar)

Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease. (yeni pencere açar)

Zimmerman SA, Schultz WH, Davis JS, Pickens CV, Mortier NA, Howard TA, Ware RE.

Kaynak‎: Blood 2004;103(6):2039-45.

İndeks‎: PubMed 14630791

DOI‎: 10.1182/blood-2003-07-2475

https://www.ncbi.nlm.nih.gov/pubmed/14630791 (yeni pencere açar)

Enfeksiyonların ve Başka Komplikasyonların Önlenmesi

Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease. (yeni pencere açar)

Hirst C, Owusu-Ofori S.

Kaynak‎: Cochrane Database Syst Rev 2012;(9):CD003427.

İndeks‎: PubMed 22972063

DOI‎: 10.1002/14651858.CD003427.pub2

https://www.ncbi.nlm.nih.gov/pubmed/22972063 (yeni pencere açar)

Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial. (yeni pencere açar)

Howard J, Ataga KI, Brown RC, Achebe M, Nduba V, El-Beshlawy A, Hassab H, Agodoa I, Tonda M, Gray S, Lehrer-Graiwer J, Vichinsky E

Kaynak‎: Lancet Haematol 2021;8(5):e323-33.

İndeks‎: PubMed 33838113

DOI‎: 10.1016/S2352-3026(21)00059-4

https://www.ncbi.nlm.nih.gov/pubmed/33838113 (yeni pencere açar)

Sickle cell disease. (yeni pencere açar)

Meremikwu MM, Okomo U.

Kaynak‎: BMJ Clin Evid 2011;02:2402.

İndeks‎: PubMed 21718552

https://www.ncbi.nlm.nih.gov/pubmed/21718552 (yeni pencere açar)

A phase 3 trial of l-glutamine in sickle cell disease. (yeni pencere açar)

Niihara Y, Miller ST, Kanter J, Lanzkron S, Smith WR, Hsu LL, Gordeuk VR, Viswanathan K, Sarnaik S, Osunkwo I, Guillaume E, Sadanandan S, Sieger L, Lasky JL, Panosyan EH, Blake OA, New TN, Bellevue R, Tran LT, Razon RL, Stark CW, Neumayr LD, Vichinsky EP

Kaynak‎: N Engl J Med 2018;379(3):226-35.

İndeks‎: PubMed 30021096

DOI‎: 10.1056/NEJMoa1715971

https://www.ncbi.nlm.nih.gov/pubmed/30021096 (yeni pencere açar)

Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa. (yeni pencere açar)

Olupot-Olupot P, Tomlinson G, Williams TN, Tshilolo L, Santos B, Smart LR, McElhinney K, Howard TA, Aygun B, Stuber SE, Lane A, Latham TS, Ware RE

Kaynak‎: Blood. 2023 23;141(12):1402-10.

İndeks‎: PubMed 36375125

DOI‎: 10.1182/blood.2022017051

https://pubmed.ncbi.nlm.nih.gov/36375125/ (yeni pencere açar)

Malaria chemoprophylaxis in sickle cell disease. (yeni pencere açar)

Oniyangi O, Omari AA.

Kaynak‎: Cochrane Database Syst Rev 2006;(4):CD003489.

İndeks‎: PubMed 17054173

DOI‎: 10.1002/14651858.CD003489.pub2

https://www.ncbi.nlm.nih.gov/pubmed/17054173 (yeni pencere açar)