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輕度和中度乙型(β)地中海貧血(兒科)

經由藥物誘導體內胎兒血紅蛋白的合成

羥基脲(Hydrea)療法

Optimizing the dose of hydroxyurea therapy for patients with β-thalassemia intermedia (Hb E-β-thalassemia): a single center study from eastern India. (開啟新視窗)

Bohara VV, Ray S, Chakrabarti P, Ray SS, Nath UK, Chaudhuri U.

出處‎: Hemoglobin 2014;38(1):44-8.

檢索‎: PubMed 24144212

DOI碼‎: 10.3109/03630269.2013.845844

https://www.ncbi.nlm.nih.gov/pubmed/24144212 (開啟新視窗)

Hydroxyurea in thalassemia intermedia--a promising therapy. (開啟新視窗)

Dixit A, Chatterjee TC, Mishra P, Choudhry DR, Mahapatra M, Tyagi S, Kabra M, Saxena R, Choudhry VP.

出處‎: Ann Hematol 2005;84(7):441-6.

檢索‎: PubMed 15838670

DOI碼‎: 10.1007/s00277-005-1026-4

https://www.ncbi.nlm.nih.gov/pubmed/15838670 (開啟新視窗)

Effect of hydroxyurea on the transfusion requirements in patients with severe HbE-beta-thalassaemia: a genotypic and phenotypic study. (開啟新視窗)

Italia KY, Jijina FF, Merchant R, Panjwani S, Nadkarni AH, Sawant PM, Nair SB, Ghosh K, Colah RB.

出處‎: J Clin Pathol 2010;63(2):147-50.

檢索‎: PubMed 20154037

DOI碼‎: 10.1136/jcp.2009.070391

https://www.ncbi.nlm.nih.gov/pubmed/20154037 (開啟新視窗)

Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia. (開啟新視窗)

Karimi M, Mohammadi F, Behmanesh F, Samani SM, Borzouee M, Amoozgar H, Haghpanah S.

出處‎: Eur J Haematol 2010;84(1):52-8.

檢索‎: PubMed 19799627

DOI碼‎: 10.1111/j.1600-0609.2009.01356.x

https://www.ncbi.nlm.nih.gov/pubmed/19799627 (開啟新視窗)

Single and combination drug therapy for fetal hemoglobin augmentation in hemoglobin E-beta 0-thalassemia: Considerations for treatment. (開啟新視窗)

Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP.

出處‎: Ann N Y Acad Sci 2005;1054:250-6.

檢索‎: PubMed 16339672

DOI碼‎: 10.1196/annals.1345.031

https://www.ncbi.nlm.nih.gov/pubmed/16339672 (開啟新視窗)

基因重組紅血球生成素(單獨給予或合併其他製劑)

Treatment of beta-thalassemia patients with recombinant human erythropoietin: effect on transfusion requirements and soluble adhesion molecules. (開啟新視窗)

Chaidos A, Makis A, Hatzimichael E, Tsiara S, Gouva M, Tzouvara E, Bourantas KL.

出處‎: Acta Haematol 2004;111(4):189-95.

檢索‎: PubMed 15153710

DOI碼‎: 10.1159/000077551

https://www.ncbi.nlm.nih.gov/pubmed/15153710 (開啟新視窗)

Darbepoetin alfa for the treatment of anaemia in alpha- or beta- thalassaemia intermedia syndromes. (開啟新視窗)

Singer ST, Vichinsky EP, Sweeters N, Rachmilewitz E.

出處‎: Br J Haematol 2011;154(2):281-4.

檢索‎: PubMed 21496003

DOI碼‎: 10.1111/j.1365-2141.2011.08617.x

https://www.ncbi.nlm.nih.gov/pubmed/21496003 (開啟新視窗)

The emerging role of fetal hemoglobin induction in non-transfusion-dependent thalassemia. (開啟新視窗)

Thein SL.

出處‎: Blood Rev 2012;26 Suppl 1:S35-9.

檢索‎: PubMed 22631042

DOI碼‎: 10.1016/S0268-960X(12)70011-5

https://www.ncbi.nlm.nih.gov/pubmed/22631042 (開啟新視窗)

其他製劑

Fetal hemoglobin inducers from the natural world: a novel approach for identification of drugs for the treatment of {beta}-thalassemia and sickle-cell anemia. (開啟新視窗)

Bianchi N, Zuccato C, Lampronti I, Borgatti M, Gambari R.

出處‎: Evid Based Complement Alternat Med 2009;6(2):141-51.

檢索‎: PubMed 18955291

DOI碼‎: 10.1093/ecam/nem139

https://www.ncbi.nlm.nih.gov/pubmed/18955291 (開啟新視窗)

A randomized phase I/II trial of HQK-1001, an oral fetal globin gene inducer, in β-thalassaemia intermedia and HbE/β-thalassaemia. (開啟新視窗)

Fucharoen S, Inati A, Siritanaratku N, Thein SL, Wargin WC, Koussa S, Taher A, Chaneim N, Boosalis M, Berenson R, Perrine SP.

出處‎: Br J Haematol 2013;161(4):587-93.

檢索‎: PubMed 23530969

DOI碼‎: 10.1111/bjh.12304

https://www.ncbi.nlm.nih.gov/pubmed/23530969 (開啟新視窗)

Butyric acid: what is the future for this old substance? (開啟新視窗)

Sossai P.

出處‎: Swiss Med Wkly 2012;142:w13596.

檢索‎: PubMed 22674349

DOI碼‎: 10.4414/smw.2012.13596

https://www.ncbi.nlm.nih.gov/pubmed/22674349 (開啟新視窗)